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Your search keyword '"Isao Okazaki"' showing total 3 results
Start Over Author "Isao Okazaki" Publisher bentham science publishers ltd.
3 results on '"Isao Okazaki"'

1. Meet Our Regional Editor

Author

Isao Okazaki

Subjects
0301 basic medicine, Pharmacology, 03 medical and health sciences, Cancer Research, 030104 developmental biology, 0302 clinical medicine, business.industry, 030220 oncology & carcinogenesis, Molecular Medicine, Medicine, business
Published
2018
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2. Introduction: MMPs, ADAMs/ADAMTSs Research Products to Achieve Big Dream

Author

Kazuki Nabeshima and Isao Okazaki

Subjects
Pharmacology, Cancer Research, business.industry, Cancer, Antineoplastic Agents, Tissue Inhibitor of Metalloproteinases, Matrix metalloproteinase, medicine.disease, Matrix Metalloproteinases, Metastasis, Cancer treatment, Gene Expression Regulation, Neoplastic, ADAM Proteins, Neoplasms, medicine, Cancer research, Animals, Humans, Molecular Medicine, Tumor growth, business, Signal Transduction
Abstract

Matrix metalloproteinases (MMPs) are known to participate in cancer invasion and metastasis. Copious research on MMPs and their inhibitors has promoted the understanding of the mechanisms of cancer invasion and metastasis as well as the development of effective drugs for cancer treatment. This review discusses the classification of MMPs and tissue inhibitors of metalloproteinases (TIMPs) in relation to tumor growth and invasion mechanisms via signal transduction, followed by the possibilities for cancer treatment. The review focuses especially on the development of anti-cancer agents in the field of MMP science.

Published
2012
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