1. Long-term survival after enucleation of a giant esophageal gastrointestinal stromal tumor
- Author
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Hao Wu, Gang Hui, Yuancai Xie, Hai Zhang, Xuxing Peng, Baokun Chen, Zhimin Mu, Jixian Liu, Da Wu, and Yiwang Ye
- Subjects
Adult ,Male ,medicine.medical_specialty ,Time Factors ,Esophageal Neoplasms ,Gastrointestinal Stromal Tumors ,Biopsy ,medicine.medical_treatment ,DNA Mutational Analysis ,Enucleation ,Case Report ,Physical examination ,PDGFRA ,Endosonography ,Predictive Value of Tests ,Biomarkers, Tumor ,medicine ,Humans ,Thoracotomy ,Esophagus ,GiST ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,General Medicine ,Esophageal Gastrointestinal Stromal Tumor ,Immunohistochemistry ,digestive system diseases ,Tumor Burden ,Surgery ,Esophagectomy ,Treatment Outcome ,medicine.anatomical_structure ,Mutation ,Neoplasm Grading ,Tomography, X-Ray Computed ,business - Abstract
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms of the gastrointestinal tract. Less than 1% occurs in the esophagus. Surgery is the primary treatment for patients with GISTs. We report a 29-year-old male was admitted after the detection of a posterior mediastinal mass during work-up with routine examination. He did not have any disease-related symptoms. The physical examination was unremarkable. Chest computed tomographic scan, the barium esophagogram and endoscopic esophageal ultrasound showed benign neoplasm. The patient was performed an enucleation surgery through the right posterolateral thoracotomy. The pathology revealed a 13.0 cm × 12.0 cm × 5.0 cm mass. The tumor was CD117 (C-kit), PDGFRA and DOG1 positive. These findings were consistent with a GIST of the esophagus. So the diagnosis of GIST of esophagus was confirmed. The pathological diagnosis of low grade of GIST of esophagus was confirmed. The patient has no evidence of recurrence and is in good clinical conditions up-to date, five years after surgery.
- Published
- 2014
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