1. Cabazitaxel in castration resistant prostate cancer with brain metastases: 3 case reports
- Author
-
Tania Policastro, Piera Federico, Giuseppe Di Lorenzo, Livio Puglia, Sabino De Placido, Pasquale Rescigno, Michela Izzo, Davide Bosso, and Carlo Buonerba
- Subjects
Oncology ,medicine.medical_specialty ,business.industry ,Whole brain radiotherapy ,Case Report ,General Medicine ,Castration resistant ,Malignancy ,medicine.disease ,Clinical Practice ,Prostate cancer ,Clinical history ,Clinical evidence ,Cabazitaxel ,Internal medicine ,medicine ,business ,medicine.drug - Abstract
Prostate cancer is the most common non-cutaneous malignancy for men. The skeleton is the most common metastatic site but, following an improvement in survival, metastases in uncommon sites are being found more frequently in clinical practice, especially brain metastases. Despite the new drugs now available for metastatic castration resistant prostate cancer, no clinical evidence exists about their effectiveness on brain metastases. We describe the clinical history of 3 patients treated with cabazitaxel plus whole brain radiotherapy. These case reports demonstrate that cabazitaxel is highly active and well tolerated in brain metastases.
- Published
- 2014