1. Doege-Potter syndrome by malignant solitary fibrous tumor of the liver: A case report and review of literature
- Author
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Maria Conticchio, Stefano Lafranceschina, Loren Duda, Umberto Riccelli, Anna Colagrande, Bianca Pascazio, Antonella Cristofano, Felicia Fiore, Leonardo Resta, Riccardo Memeo, and Antonella Delvecchio
- Subjects
Mesenchymal tumor ,medicine.medical_specialty ,Solitary fibrous tumor ,Pathology ,business.industry ,Mesenchymal Tumor ,Doege-Potter syndrome ,Malignant Solitary Fibrous Tumor ,Case Report ,medicine.disease ,Hepatic tumor ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,Malignant solitary fibrous tumor of the liver ,030220 oncology & carcinogenesis ,medicine ,030211 gastroenterology & hepatology ,Doege–Potter syndrome ,business - Abstract
BACKGROUND Solitary fibrous tumor of the liver (SFTL) is a rare occurrence with a low number of cases reported in literature. SFTL is usually benign but, 10%-20% cases are reported to be malignant with a tendency to metastasize. The majority of malignant SFTL cases are associated with a paraneoplastic hypoglycaemia defined as Doege-Potter syndrome. Surgery is the best therapeutic treatment, however, long- life follow-up is recommended. CASE SUMMARY A 74-year-old man, was admitted to the emergency department after a syncopal episode with detection of hypoglycaemia resistant to medical treatment. The computed tomography revealed a solid mass measuring 15 cm of the left liver. An open left hepatectomy was performed with complete resection of tumor. Histopathological analyses confirmed a malignant SFTL. CONCLUSION Large series with long-term follow-up have not been published neither have clinical trials been undertaken. Consequently, the methodical long-term follow-up of surgically treated SFTLs is strongly recommended.
- Published
- 2019