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Objective: Invasive infections caused by group A streptococci, including bacteremia, pneumonia, sepsis, necrotizing fasciitis, streptococcal toxic shock syndrome, and focal infections, are the significant causes of mortality and morbidity worldwide. This study aimed to assess the clinical and laboratory features and management of children with invasive group A streptococci infections. Materials and Methods: A descriptive observational study was conducted on children younger than 18 years with invasive group A streptococci infection in a single center between 2012 and 2019. The clinical and laboratory features, treatment options, and patient outcomes were evaluated retrospectively. Results: Forty-nine patients diagnosed with an invasive group A streptococci infection were analyzed. Among them, 28 (57.1%) were boys and 21 (42.9%) were girls, with a median age of 84 months (IQR: 48-150). Group A streptococci strains were found to be isolated mainly from the skin and soft tissue abscesses (60.7%). It was found that 21 (42.9%) of the cases were hospitalized, and the median duration of hospitalization was 7 (IQR: 5-11) days. It was noted that all of the cases were treated, and infection-related mortality was not observed in any patient. Conclusions: For correct management of invasive group A streptococci infections, timely diagnosis, appropriate duration of antimicrobial therapy, and surgical intervention in selected cases are required. It is thought that examining this issue in future studies may provide clues regarding the localization, severity, management of the infection clinic, and treatment. [ABSTRACT FROM AUTHOR]

Aim: The aim of this study was to evaluate the quality of sleep in mothers of children with bronchiolitis obliterans. Material and Method: The study group consisted of 36 mothers with a child who had bronchiolitis obliterans and 62 mothers with healthy children. All mothers enrolled in the study filled in the Pittsburgh Sleep Quality Index (PSQI). Results: The mean ages of the children of the mothers enrolled in the study were statistically similar (3.57±2.58 vs 3.85±1.46 years, p>0.05). Total Pittsburgh Sleep Quality Index scores and subjective sleep quality scores in the mothers of children with bronchiolitis obliterans were significantly higher than those in the mothers of healthy children (both p=0.015). Conclusions: In this study, it was found that mothers of children with bronchiolitis obliterans have poor sleep quality. Therefore, assessment may be needed for the requirement of support regarding sleep quality in them. [ABSTRACT FROM AUTHOR]