1. [The use of anticholinergic drugs and associated factors in middle-aged adults and the elderly].
- Author
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Pinto ECP, Silva AMR, Cabrera MAS, Baldoni AO, Alfieri DF, Andrade GF, and Girotto E
- Subjects
- Aged, Cross-Sectional Studies, Hospitalization, Humans, Middle Aged, Cholinergic Antagonists adverse effects, Polypharmacy
- Abstract
The objective of this article was to describe the use of anticholinergic drugs and possible factors associated with their use, in middle-aged adults and in the elderly. This is a cross-sectional study, based on data from a population-based study called VIGICARDIO. All respondents aged 44 or older interviewed in 2015 were included. Anticholinergic Drug Scale (ADS) was used to determine anticholinergic burden (ACB), categorized as significant (≥3) and non-significant (< 3). Poisson regression was conducted with crude and adjusted analysis to investigate the factors associated with ACB. There was a prevalence of 20.7% of significant ACB among respondents, higher among middle-aged adults (24.1%). After adjusted analysis, significant ACB (≥ 3) remained in the non-elderly age group with polypharmacy and sporadic use of two or more drugs. In the elderly, sporadic use of two or more medications and hospitalization in the last year continued to be associated with significant ACB. The results indicate a higher prevalence of ACB among middle-aged adults, polymedicated and in sporadic use of medications, which suggests that the investigation of the use of anticholinergicsin this age group requires greater attention.
- Published
- 2022
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