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Ｔｈｅ ｎｏｎ⁃Ｎｅｗｔｏｎｉａｎ ｔｒａｎｓｉｅｎｔ ｂｌｏｏｄ ｆｌｏｗ ｗｉｔｈ ｆｌｕｉｄ⁃ｓｔｒｕｃｔｕｒｅ ｉｎｔｅｒａｃｔｉｏｎ ｗａｓ ｎｕｍｅｒｉｃａｌｌｙ ｓｉｍｕｌａｔｅｄ ｆｏｒ ６ ｓｔｅｎｏｓｉｓ ｒａｔｉｏｓ ｏｆ ｃａｒｏｔｉｄ ａｒｔｅｒｉｅｓ ｗｉｔｈ ｔｈｅ ｃｏｍｐｕｔａｔｉｏｎａｌ ｆｌｕｉｄ ｄｙｎａｍｉｃｓ ｍｅｔｈｏｄ． Ｔｈｅ ｅｆｆｅｃｔｓ ｏｆ ｔｈｅ ｃａｒｏｔｉｄ ａｒｔｅｒｙ ｓｔｅｎｏｓｉｓ ｒａｔｉｏ ｏｎ ｔｈｅ ｈｅｍｏｄｙｎａｍｉｃ ｐｅｒｆｏｒｍａｎｃｅ ｗｅｒｅ ｉｎｖｅｓｔｉｇａｔｅｄ ｔｏ ｃｌａｒｉｆｙ ｔｈｅ ｒｅｌａｔｉｏｎｓｈｉｐ ｂｅｔｗｅｅｎ ｔｈｅ ｓｔｅｎｏｓｉｓ ｒａｔｉｏ ａｎｄ ｔｈｅ ａｔｈｅｒｏｓｃｌｅｒｏｔｉｃ ｐｌａｑｕｅ ｆｏｒｍａｔｉｏｎ ａｎｄ ｄｅｖｅｌｏｐｍｅｎｔ ｉｎ ｔｈｅ ｃａｒｏｔｉｄ ａｒｔｅｒｙ． Ｔｈｅ ｒｅｓｕｌｔｓ ｓｈｏｗ ｔｈａｔ， ｄｉｆｆｅｒｅｎｔ ｓｔｅｎｏｓｉｓ ｒａｔｉｏｓ ｏｆ ｔｈｅ ｃａｒｏｔｉｄ ａｒｔｅｒｙ ｒｅｓｕｌｔ ｉｎ ｏｂｖｉｏｕｓｌｙ ｄｉｓｓｉｍｉｌａｒ ｈｅｍｏｄｙｎａｍｉｃ ｃｈａｒａｃｔｅｒｉｓｔｉｃ ｄｉｓｔｒｉｂｕｔｉｏｎｓ． Ｃｏｍｐａｒｅｄ ｗｉｔｈ ｔｈｅ ｓｔｅｎｏｓｉｓ ｒａｔｉｏｓ ｏｆ ０．０５， ０．１， ０．２， ０．３ ａｎｄ ０．４， ｔｈｅ ｓｔｅｎｏｓｉｓ ｒａｔｉｏ ｏｆ ０．５ ｃｏｒｒｅｓｐｏｎｄｓ ｔｏ ｓｔｒｉｋｉｎｇｌｙ ｌａｒｇｅｒ ｂｌｏｏｄ ｓｔａｇｎａｎｔ ｖｏｒｔｅｘ ｆｌｏｗ ｚｏｎｅｓ ａｒｏｕｎｄ ｔｈｅ ｓｔｅｎｏｔｉｃ ｓｅｃｔｉｏｎ． Ｕｎｄｅｒ ｔｈｅ ａｃｔｉｏｎ ｏｆ ｔｈｅ ｃｏｍｐｌｅｘ ｂｏｏｄ ｆｌｏｗ ｆｉｅｌｄ， ｌｏｗｅｒ ｗａｌｌ ｐｒｅｓｓｕｒｅ， ａｂｎｏｒｍａｌ ｗａｌｌ ｓｈｅａｒ ｓｔｒｅｓｓ ｄｉｓｔｒｉｂｕｔｉｏｎ， ｌａｒｇｅｒ ｔｏｔａｌ ｍｅｓｈ ｄｉｓｐｌａｃｅｍｅｎｔ ａｎｄ ｈｉｇｈｅｒ ｖｏｎ Ｍｉｓｅｓ ｓｔｒｅｓｓ ｗｉｌｌ ｏｃｃｕｒ ａｒｏｕｎｄ ｔｈｉｓ ｓｅｃｔｉｏｎ， ｗｈｅｒｅ ｔｈｅ ｌｉｐｉｄ ａｎｄ ｆｉｂｒｉｎ ｍａｃｒｏｍｏｌｅｃｕｌｅｓ ｍａｙ ｅａｓｉｌｙ ｄｅｐｏｓｉｔ ｄｕｅ ｔｏ ｌｏｗ⁃ｓｐｅｅｄ ｂｌｏｏｄ ｆｌｏｗ． Ｍｅａｎｗｈｉｌｅ， ｌｏｗ ｗａｌｌ ｐｒｅｓｓｕｒｅ ｍａｙ ｃａｕｓｅ ｏｂｖｉｏｕｓ ‘ｎｅｇａｔｉｖｅ ｐｒｅｓｓｕｒｅ’ ｅｆｆｅｃｔｓ， ａｎｄ ｉｎ ｔｕｒｎ ｉｎｓｕｆｆｉｃｉｅｎｔ ｂｌｏｏｄ ｓｕｐｐｌｙ ｆｏｒ ｂｒａｉｎ． Ｆｕｒｔｈｅｒｍｏｒｅ， ｔｈｅ ａｔｈｅｒｏｓｃｌｅｒｏｔｉｃ ｐｌａｑｕｅｓ ａｒｅ ｌｉａｂｌｅ ｔｏ ｒｕｐｔｕｒｅ ａｎｄ ｆａｌｌ ｏｆｆ ｕｎｄｅｒ ａｂｎｏｒｍａｌ ｗａｌｌ ｓｈｅａｒ ｓｔｒｅｓｓ ｄｉｓｔｒｉｂｕｔｉｏｎ， ａｎｄ ｃｏｎｓｅｑｕｅｎｔｌｙ ｂｌｏｃｋ ｔｈｅ ｂｌｏｏｄ ｖｅｓｓｅｌ ｉｎ ｂｒａｉｎ． Ｌａｒｇｅ ｖａｓｃｕｌａｒ ｖｏｎ Ｍｉｓｅｓ ｓｔｒｅｓｓ ｍａｙ ｃａｕｓｅ ｓｔｒｅｓｓ ｃｏｎｃｅｎｔｒａｔｉｏｎ ａｎｄ ｒｕｐｔｕｒｅ ｏｆ ｂｌｏｏｄ ｖｅｓｓｅｌ， ｐｒｏｖｉｄｉｎｇ ｆａｖｏｒａｂｌｅ ｃｏｎｄｉｔｉｏｎｓ ｆｏｒ ｔｈｅ ｏｃｃｕｒｒｅｎｃｅ ｏｆ ｓｔｒｏｋｅ． Ｔｈｅｒｅｆｏｒｅ， ｔｈｅ ｌａｒｇｅｒ ｓｔｅｎｏｓｉｓ ｒａｔｉｏ ｔｈｅ ｃａｒｏｔｉｄ ａｒｔｅｒｙ ｈａｓ， ｔｈｅ ｇｒｅａｔｅｒ ｔｈｅ ｉｎｆｌｕｅｎｃｅ ｉｓ ｏｎ ｔｈｅ ｆｏｒｍａｔｉｏｎ ａｎｄ ｄｅｖｅｌｏｐｍｅｎｔ ｏｆ ａｔｈｅｒｏｓｃｌｅｒｏｔｉｃ ｐｌａｑｕｅｓ，ａｎｄ ｔｈｅ ｈｉｇｈｅｒ ｔｈｅ ｐｏｓｓｉｂｉｌｉｔｙ ｏｆ ｃｅｒｅｂｒａｌ ｉｓｃｈｅｍｉｃ ｓｔｒｏｋｅ ｏｃｃｕｒｓ． [ABSTRACT FROM AUTHOR]