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Introduction: The reasons of anemia seen in patients with chronic (CRF) Include eritropoeitln deficiency-resistance, iron deficiency and üremic toxins. Elevated PTH levels play a role in resistance to EPO's effect. Cinecalcet is successfully used in secondary hyperparatiroidism. The control of hyperparatiroidism can contribute to diminishing of resistance to EPO and to sooner acquiring of target hemoglobin levels. Because of this the effect of cinecalcet on hemoglobin levels has been researched Material and Methods: The dialysis patients given cinecalcet are the study group and the patients not given cinecalcet are the control group. The study included 24 patients. The acceptance criterias to the study are patients Kt/V hemodialysis >1.2 for peritone dialysis, ferritin levels> 200, transferrin saturation > %20 and PTH >300 pg/ml. The index of eritropoeitin resistance at the beginning and at the end of 3 months, hemoglobine, the EPO dosage IU/kg/week is recorded. The data Is compared with appropriate statistical methods. Results: The dialysis age, Kt/V, Ca, P, CaxP, Hb values were similar at the beginning and after 3 months in both groups. The rises of Hb in the groups are meaningful. The PTH levels of the cinecalcet given group, at the beginning and after 3 months, are meaningfully higher than the control group (p<0.00019. There was no meaningful difference in EPO and ERI indexes of the groups. Conclusion: In this study no prominent effect of cinecalcet on anemia is detected in the cinecalcet group. For this purpose prospective studies of larger series are needed. [ABSTRACT FROM AUTHOR]

Thyroid tuberculosis is a rare condition, even in the populations with high prevalence of tuberculosis. It shows different clinical course, and may be asymptomatic. The incidence of thyroid tuberculosis was reported as 0.003%-0.1% in a postmortem study, however, its real incidence is not known exactly. Therefore, diagnosis of the disease may be overlooked or delayed. Consequently, it may present as an advanced stage disease with increased morbidity and mortality. Primary thyroid tuberculosis that presented with rapidly enlarging goiter together with cervical lymphadenopathy without pulmonary involvement was first reported in 1893. Fine needle aspiration biopsy together with acido-resistant staining of the aspiration material and the culture are quite valuable in the diagnosis of the disease. In this paper, we will discuss a case of thyroid tuberculosis with graves and hypoactive nodule, which diagnosed by histopathological examination of postoperative thyroidectomy material. [ABSTRACT FROM AUTHOR]

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Aim: The aim of this study is to investigate endothelial dysfunction in psoriasis patients with non-invasive methods. Materials and Methods: Fifty-three psoriasis patients and 53 healthy individuals were included in the study. Carotid artery intimae-media thickness and brachial artery flow-mediated dilation was measured both in patient and control groups. Results: Mean age, gender, body mass index, smoking habits, anthropometric measurements and arterial blood pressure values were similar in both groups. Mean psoriasis area and severity index score of psoriasis patients was 6.35±6.81. Triglyceride level was significantly higher (p<0.05) and high density lipoprotein cholesterol level was significantly lower (p <0.05) in psoriasis patients when compared with the controls. Insulin resistance was found to be statistically higher in psoriasis patients group than the control group (p<0.05). There was no significant differences between two groups in terms of carotid artery intimae-media thickness (p>0.05); but flow-mediated dilation was found to be statistically significantly lower in psoriasis patients than the control group (p<0.05). FT3 level was also found to be statistically significantly lower in psoriasis patients than the control group (p=0.05). Conclusion: This study showed endothelial dysfunction and insulin resistance in psoriasis patients with low disease activity even in the absence of clinical cardiovascular disease. Thyroid function tests could supply information about cardiovascular risk. [ABSTRACT FROM AUTHOR]