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PURPOSE Health Teams Advancing Patient Experience: Strengthening Quality (Health TAPESTRY) is a complex primary care program aimed at assisting older adults to stay healthier for longer. This study evaluated the feasibility of implementation across multiple sites, and the reproducibility of the effects found in the previous randomized controlled trial. METHODS This was a pragmatic, unblinded, 6-month parallel group randomized controlled trial. Participants were randomized (intervention or control) using a computer-generated system. Eligible patients, aged 70 years and older, were rostered to 1 of 6 participating interprofessional primary care practices (urban and rural). In total, 599 (301 intervention, 298 control) patients were recruited from March 2018 through August 2019. Intervention participants received a home visit from volunteers to collect information on physical and mental health, and social context. An interprofessional care team created and implemented a plan of care. The primary outcomes were physical activity and number of hospitalizations. RESULTS Based on the Reach, Effectiveness, Adoption, Implementation, Maintenance (REAIM) framework, Health TAPESTRY had widespread reach and adoption. In the intention-totreat analysis (257 intervention, 255 control), there were no statistically significant betweengroup differences for hospitalizations (incidence rate ratio = 0.79; 95% CI, 0.48-1.30; P = .35) or total physical activity (mean difference = -0.26; 95% CI, -1.18 to 0.67; P = .58). There were 37 non-study related serious adverse events (19 intervention, 18 control). CONCLUSIONS We found Health TAPESTRY was successfully implemented for patients in diverse primary care practices; however, implementation did not reproduce the effect on hospitalizations and physical activity found in the initial randomized controlled trial. [ABSTRACT FROM AUTHOR]

The article presents a research which examines the cumulative risk of a false-positive screening result and the resulting risk of a diagnostic procedure for an individual participating in multimodal cancer screening. There were 68,436 participants aged 55 to 74 years that were randomized to screening. It was found that the risk of a false-positive finding is more than 50 percent in individuals with multimodal cancer screening trial.

The article presents a study that examines the integration of depression treatment into care for hypertension among older primary care patients. The researchers employed randomized controlled trials on older adults under care for hypertension in West Philadelphia, and were subjected to an integrated care intervention or usual care. Results indicated improvement in patient outcomes using depression and hypertension treatment procedure.