1. [Shigella serotypes and drug resistance patterns of strains isolated in Etimesgut, Turkey, in 1987].
- Author
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Korten V, Mert A, Ovünç K, Ceyhan M, Acar S, and Ulaş T
- Subjects
- Ampicillin Resistance, Ceftriaxone pharmacology, Chloramphenicol Resistance, Drug Resistance, Microbial, Humans, Nalidixic Acid pharmacology, Ofloxacin pharmacology, Prospective Studies, Serotyping, Shigella drug effects, Shigella boydii classification, Shigella boydii drug effects, Shigella flexneri classification, Shigella flexneri drug effects, Shigella sonnei classification, Shigella sonnei drug effects, Streptomycin pharmacology, Tetracycline Resistance, Trimethoprim, Sulfamethoxazole Drug Combination pharmacology, Turkey, Anti-Bacterial Agents pharmacology, Dysentery, Bacillary microbiology, Shigella classification
- Abstract
Drug resistance patterns of shigella strains were investigated in a prospective manner in Etimesgut district during a period of 1 year. Thirty strains shigella were isolated, belonged to three subgroups with preponderance of Sh. flexneri (70%), followed by Sh. sonnei (27%) and Sh. boydii (3%). The resistance was highest with streptomycin (80%), followed by trimethoprim-sulfamethoxazole (TMP-SMZ) (53%) and ampicillin (43%). Only three strains (10%) were sensitive to all eight antibiotics tested. Sixteen (53%) were resistant to three or more antibiotics. The data showed an increase in resistance to the commonly used antimicrobial agents--namely IMP-SMZ and ampicillin. IMP-SMZ is no longer the drug of choice in severe shigellosis, at least in this region of Turkey.
- Published
- 1988