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Your search keyword '"Vivek N. Ahya"' showing total 9 results
Start Over Author "Vivek N. Ahya" Publisher american thoracic society
9 results on '"Vivek N. Ahya"'

1. Patients, Caregivers, and Clinicians Describe Time-Varying Social, Behavioral, and Clinical Risk Trajectories Leading to Hospitalizations for People with Chronic Lung Disease

Author

Scott D. Halpern, Tamar Klaiman, Vivek N. Ahya, I.S. Mullen, Michael W. Sims, Joanna L. Hart, S. Kangovi, N. Bishop, Folasade C. Lapite, A. Summer, T. Kmiec, Gary E. Weissman, Jasmine A Silvestri, and J.E. Szymczak

Subjects
medicine.medical_specialty, business.industry, Lung disease, medicine, Intensive care medicine, business, Clinical risk factor
Published
2021

2. Plasma Levels of Receptor for Advanced Glycation End Products, Blood Transfusion, and Risk of Primary Graft Dysfunction

Author

Jason D, Christie, Chirag V, Shah, Steven M, Kawut, Nilam, Mangalmurti, David J, Lederer, Joshua R, Sonett, Vivek N, Ahya, Scott M, Palmer, Keith, Wille, Vibha, Lama, Pali D, Shah, Ashish, Shah, Ann, Weinacker, Clifford S, Deutschman, Benjamin A, Kohl, Ejigayehu, Demissie, Scarlett, Bellamy, Lorraine B, Ware, and Ashley, Finlen-Copeland

Subjects
Adult, Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Resuscitation, Time Factors, Blood transfusion, medicine.medical_treatment, Receptor for Advanced Glycation End Products, Blood Component Transfusion, Critical Care and Intensive Care Medicine, Gastroenterology, law.invention, Cohort Studies, law, Blood product, Intensive care, Internal medicine, Cardiopulmonary bypass, medicine, Humans, Lung transplantation, Prospective Studies, Receptors, Immunologic, Prospective cohort study, business.industry, Middle Aged, respiratory system, Surgery, Transplantation, Female, lipids (amino acids, peptides, and proteins), Primary Graft Dysfunction, business, Biomarkers, Lung Transplantation
Abstract

Rationale:Thereceptorforadvancedglycationendproducts(RAGE) is an important marker of lung epithelial injury and may be associated with impaired alveolar fluid clearance. We hypothesized that patients with primary graft dysfunction (PGD) after lung transplantation would have higher RAGE levels in plasma than patients without PGD. Objectives:TotesttheassociationofsolubleRAGE(sRAGE)levelswith PGD in a prospective, multicenter cohort study. Methods: We measured plasma levels of sRAGE at 6 and 24 hours afterallograftreperfusion in317 lungtransplantrecipientsatseven centers. The primary outcome was grade 3 PGD (PaO2 /FIO2 , 200 with alveolar infiltrates) within the first 72 hours after transplantation. Measurements and Main Results: Patients who developed PGD had higher levels of sRAGE than patients without PGD at both 6 hours (median 9.3 ng/ml vs. 7.5 ng/ml, respectively; P 5 0.028) and at 24 hours post-transplantation (median 4.3 ng/ml vs. 1.9 ng/ml, respectively; P , 0.001). Multivariable logistic regression analyses indicated that the relationship between levels of sRAGE and PGD was attenuated by elevated right heart pressures and by the use of cardiopulmonary bypass. Median sRAGE levels were higher in subjects with cardiopulmonary bypass at both 6 hours (P 5 0.003) and 24 hours (P , 0.001). sRAGE levels at 6 hours were significantly associated with intraoperative red cell transfusion (Spearman’s r 5 0.39, P 5 0.002 in those with PGD), and in multivariable linear regression analyses this association was independent of confounding variables (P 5 0.02). Conclusions: Elevated plasma levels of sRAGE are associated with PGD after lung transplantation. Furthermore, plasma sRAGE levels are associated with blood product transfusion and use of cardiopulmonary bypass.

Published
2009

3. Elevated Monocyte Chemotactic Protein-1 (MCP-1) Is Associated With Primary Graft Dysfunction Following Lung Transplantation

Author

Joshua M. Diamond, Keith M. Wille, James Lee, David S. Wilkes, David Weill, Ashish S. Shah, Jonathan B. Orens, Clifford S. Deutschman, Steven M. Kawut, Sangeeta Bhorade, David J. Lederer, Maria M. Crespo, Joshua R. Sonett, Jason D. Christie, Benjamin A. Kohl, John Reynolds, John A. Belperio, Vibha N. Lama, Ejigayehu Demissie, Edward Cantu, Ann Weinacker, Rupal J. Shah, Vivek N. Ahya, Selim M. Arcasoy, Lorraine B. Ware, Pali D. Shah, and Scott M. Palmer

Subjects
business.industry, medicine.medical_treatment, Immunology, Medicine, Primary Graft Dysfunction, Lung transplantation, CCL2, business
Published
2011

4. Mechanical Ventilation after Lung Transplantation. It’s Time for a Trial

Author

Joshua M. Diamond and Vivek N. Ahya

Subjects
Pulmonary and Respiratory Medicine, Mechanical ventilation, medicine.medical_specialty, business.industry, Ventilator-Induced Lung Injury, medicine.medical_treatment, Respiration, Artificial, medicine, Humans, Lung transplantation, Practice Patterns, Physicians', Primary Graft Dysfunction, Intensive care medicine, business, Lung Transplantation
Published
2014

5. The Effect Of Pte-transplant Obesity On Outcomes After Lung Transplant

Author

Denis Hadjiliadis, Alberto Pochettino, Robert M. Kotloff, Jason D. Christie, Molly Kaplan, James Lee, and Vivek N. Ahya

Subjects
medicine.medical_specialty, Lung, medicine.anatomical_structure, business.industry, Internal medicine, Medicine, business, medicine.disease, Obesity
Published
2010

7. Differential Effects Of Single And Bilateral Lung Transplantation On Serum Surfactant Protein D Levels In Subjects With Idiopathic Pulmonary Fibrosis

Author

Jason D. Christie, Ejigayehu Demissie, Scarlett L. Bellamy, Scott M. Palmer, Michael F. Beers, Pali D. Shah, Keith M. Wille, Vivek N. Ahya, David J. Lederer, Sangeeta Bhorade, Steven M. Kawut, Maria M. Crespo, Jonathan B. Orens, Mike Sims, Vibha N. Lama, Lorraine B. Ware, and Ann Weinacker

Subjects
Idiopathic pulmonary fibrosis, Pathology, medicine.medical_specialty, business.industry, Immunology, medicine, Surfactant protein D, Bilateral lung transplantation, medicine.disease, business, Differential effects
Published
2010

8. Elevated Plasma Clara Cell Secretory Protein Concentration Is Associated With High-Grade Primary Graft Dysfunction

Author

David J. Lederer, Vivek N. Ahya, Maria M. Crespo, Scarlett L. Bellamy, Keith M. Wille, Vibha N. Lama, Selim M. Arcasoy, Steven M. Kawut, Sangeeta Bhorade, Lorraine B. Ware, Clifford S. Deutschman, Jason D. Christie, Benjamin A. Kohl, Scott M. Palmer, David Weill, Ann Weinacker, Joshua M. Diamond, J.R. Sonett, Jonathan B. Orens, Pali D. Shah, Ashish S. Shah, and Ejigayehu Demissie

Subjects
medicine.medical_specialty, Endocrinology, Clara Cell Secretory Protein, business.industry, Internal medicine, Primary Graft Dysfunction, Medicine, business
Published
2010

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