1. Long-Term Mortality and Major Adverse Cardiovascular Events in Sepsis Survivors. A Nationwide Population-based Study
- Author
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Chia Jen Shih, Tzeng Ji Chen, Shuo Ming Ou, Shu-Chen Kuo, Yung Tai Chen, Ching Min Tseng, Hsi Ning Chu, Yi Jung Lee, and Pei Wen Chao
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,education.field_of_study ,Proportional hazards model ,business.industry ,Population ,030204 cardiovascular system & hematology ,Critical Care and Intensive Care Medicine ,medicine.disease ,Sudden cardiac death ,Sepsis ,03 medical and health sciences ,0302 clinical medicine ,Heart failure ,Epidemiology ,medicine ,030212 general & internal medicine ,Myocardial infarction ,Intensive care medicine ,business ,education ,Stroke - Abstract
Rationale: Patients with sepsis who survive to hospital discharge may present with ongoing high morbidity and mortality. However, little is known about the risk of long-term, all-cause mortality and cardiovascular outcomes after sepsis.Objectives: Our study aimed to investigate the long-term clinical outcomes in sepsis survivors.Methods: In this nationwide population-based study, data from patients with sepsis were retrieved from Taiwan’s National Health Insurance Research Database between 2000 and 2002. Each sepsis survivor was 1:1 propensity-matched to control subjects from two different control populations: subjects who were in the general population and subjects who were hospitalized for a nonsepsis diagnosis. The primary outcomes were all-cause mortality, major adverse cardiovascular events, myocardial infarction, heart failure, stroke, and sudden cardiac death or ventricular arrhythmia.Measurements and Main Results: Compared with matched population control subjects, sepsis survivors had higher risks...
- Published
- 2016