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Your search keyword '"Kim, Carla"' showing total 12 results
Start Over Author "Kim, Carla" Publisher american thoracic society
12 results on '"Kim, Carla"'

1. Human Airway and Alveolar Organoids from Bronchoalveolar Lavage Fluid

Author

Liu, Monica Yun, primary, Chen, Belinda, additional, Borji, Mehdi, additional, Garcia de Alba Rivas, Carolina, additional, Dost, Antonella F. M., additional, Moye, Aaron L., additional, Movval Abdulla, Nusrath, additional, Paschini, Margherita, additional, Rollins, Stuart D., additional, Wang, Ruobing, additional, Schnapp, Lynn M, additional, Khalil, Hassan A, additional, Wu, Catherine J., additional, Sharma, Nirmal S, additional, and Kim, Carla F, additional

Published
2024
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2. Human Airway and Alveolar Organoids from BAL Fluid.

Author

Liu, Monica Yun, Chen, Belinda, Borji, Mehdi, Garcia de Alba Rivas, Carolina, Dost, Antonella F. M., Moye, Aaron L., Movval Abdulla, Nusrath, Paschini, Margherita, Rollins, Stuart D., Wang, Ruobing, Schnapp, Lynn M., Khalil, Hassan A., Wu, Catherine J., Sharma, Nirmal S., and Kim, Carla F.

Subjects
ORGANOIDS, BRONCHOALVEOLAR lavage
Abstract

The article focuses on establishing efficient methods for deriving airway and alveolar organoids from human bronchoalveolar lavage (BAL) samples. It is reported that these organoids recapitulate diverse cell types found in the lung epithelium, offering versatile models for studying lung diseases and personalized therapeutics.

Published
2024
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4. National Heart, Lung, and Blood Institute and Building Respiratory Epithelium and Tissue for Health (BREATH) Consortium Workshop Report: Moving Forward in Lung Regeneration

Author

Hynds, Robert E., primary, Zacharias, William J., additional, Nikolić, Marko Z., additional, Königshoff, Melanie, additional, Eickelberg, Oliver, additional, Gosens, Reinoud, additional, de Coppi, Paolo, additional, Janes, Sam M., additional, Morrisey, Edward, additional, Clevers, Hans, additional, Ryan, Amy L., additional, Stripp, Barry R., additional, Sun, Xin, additional, Kim, Carla F., additional, and Lin, Qing S., additional

Published
2021
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7. The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations

Author

Agrawal, Pankaj B., primary, Wang, Ruobing, additional, Li, Hongmei Lisa, additional, Schmitz-Abe, Klaus, additional, Simone-Roach, Chantelle, additional, Chen, Jingxin, additional, Shi, Jiahai, additional, Louie, Tin, additional, Sheng, Shaohu, additional, Towne, Meghan C., additional, Brainson, Christine F., additional, Matthay, Michael A., additional, Kim, Carla F., additional, Bamshad, Michael, additional, Emond, Mary J., additional, Gerard, Norma P., additional, Kleyman, Thomas R., additional, and Gerard, Craig, additional

Published
2017
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8. Surfactant Protein–C Chromatin-Bound Green Fluorescence Protein Reporter Mice Reveal Heterogeneity of Surfactant Protein C–Expressing Lung Cells

Author

Lee, Joo-Hyeon, primary, Kim, Jonghwan, additional, Gludish, David, additional, Roach, Rebecca R., additional, Saunders, Arven H., additional, Barrios, Juliana, additional, Woo, Andrew Jonghan, additional, Chen, Huaiyong, additional, Conner, David A., additional, Fujiwara, Yuko, additional, Stripp, Barry R., additional, and Kim, Carla F., additional

Published
2013
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11. Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non-Small Cell Lung Cancer. An Official American Thoracic Society Research Statement.

Author

Moghaddam SJ, Savai R, Salehi-Rad R, Sengupta S, Kammer MN, Massion P, Beane JE, Ostrin EJ, Priolo C, Tennis MA, Stabile LP, Bauer AK, Sears CR, Szabo E, Rivera MP, Powell CA, Kadara H, Jenkins BJ, Dubinett SM, Houghton AM, Kim CF, and Keith RL

Subjects
Humans, Disease Progression, Societies, Medical, United States, Carcinoma, Non-Small-Cell Lung pathology, Carcinoma, Non-Small-Cell Lung therapy, Lung Neoplasms pathology, Lung Neoplasms therapy, Precancerous Conditions pathology, Precancerous Conditions therapy
Abstract

Rationale: Despite significant advances in precision treatments and immunotherapy, lung cancer is the most common cause of cancer death worldwide. To reduce incidence and improve survival rates, a deeper understanding of lung premalignancy and the multistep process of tumorigenesis is essential, allowing timely and effective intervention before cancer development. Objectives: To summarize existing information, identify knowledge gaps, formulate research questions, prioritize potential research topics, and propose strategies for future investigations into the premalignant progression in the lung. Methods: An international multidisciplinary team of basic, translational, and clinical scientists reviewed available data to develop and refine research questions pertaining to the transformation of premalignant lung lesions to advanced lung cancer. Results: This research statement identifies significant gaps in knowledge and proposes potential research questions aimed at expanding our understanding of the mechanisms underlying the progression of premalignant lung lesions to lung cancer in an effort to explore potential innovative modalities to intercept lung cancer at its nascent stages. Conclusions: The identified gaps in knowledge about the biological mechanisms of premalignant progression in the lung, together with ongoing challenges in screening, detection, and early intervention, highlight the critical need to prioritize research in this domain. Such focused investigations are essential to devise effective preventive strategies that may ultimately decrease lung cancer incidence and improve patient outcomes.

Published
2024
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12. Stem cells and cell therapies in lung biology and lung diseases.

Author

Weiss DJ, Bertoncello I, Borok Z, Kim C, Panoskaltsis-Mortari A, Reynolds S, Rojas M, Stripp B, Warburton D, and Prockop DJ

Subjects
Adaptive Immunity, Animals, Bioengineering, Clinical Trials as Topic, Disease Models, Animal, Epithelial Cells physiology, Humans, Immunity, Innate, Lung cytology, Lung physiology, Regeneration, Stem Cell Research ethics, Terminology as Topic, Tissue Engineering, Tissue Scaffolds, Lung Diseases therapy, Stem Cells physiology
Abstract

The University of Vermont College of Medicine and the Vermont Lung Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the Alpha-1 Foundation, the American Thoracic Society, the Emory Center for Respiratory Health,the Lymphangioleiomyomatosis (LAM) Treatment Alliance,and the Pulmonary Fibrosis Foundation, convened a workshop,‘‘Stem Cells and Cell Therapies in Lung Biology and Lung Diseases,’’ held July 26-29, 2009 at the University of Vermont,to review the current understanding of the role of stem and progenitor cells in lung repair after injury and to review the current status of cell therapy approaches for lung diseases. These are rapidly expanding areas of study that provide further insight into and challenge traditional views of the mechanisms of lung repair after injury and pathogenesis of several lung diseases. The goals of the conference were to summarize the current state of the field, discuss and debate current controversies, and identify future research directions and opportunities for both basic and translational research in cell-based therapies for lung diseases.

Published
2011
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