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Start Over Author "Sandra L. Wootton-Gorges" Publisher american society of neuroradiology (asnr)
1 results on '"Sandra L. Wootton-Gorges"'

1. Progressive Decrease inN-Acetylaspartate/Creatine Ratio in a Teenager with Type 1 Diabetes and Repeated Episodes of Ketoacidosis without Clinically Apparent Cerebral Edema: Evidence for Permanent Brain Injury: Fig 1

Author

Michael H. Buonocore, Sandra L. Wootton-Gorges, Nathan Kuppermann, Ryan Caltagirone, and Nicole Glaser

Subjects
Type 1 diabetes, medicine.medical_specialty, endocrine system diseases, business.industry, Metabolic disorder, nutritional and metabolic diseases, Brain damage, medicine.disease, Creatine, Ketoacidosis, Cerebral edema, Central nervous system disease, chemistry.chemical_compound, Endocrinology, nervous system, chemistry, Diabetes mellitus, Internal medicine, medicine, Cardiology, Radiology, Nuclear Medicine and imaging, Neurology (clinical), medicine.symptom, business
Abstract

Recent data suggest that DKA may contribute to cognitive impairment in children with type 1 DM. We measured the NAA/Cr ratio in a teenager during and following 2 separate episodes of DKA without clinically apparent cerebral edema. The NAA/Cr ratio decreased during DKA and improved following recovery. However, the NAA/Cr value was lower after the second episode of DKA (1.76) than after the first (1.97). These findings provide support for the hypothesis that neuronal injury may result from DKA.

Published
2009
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