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30 results on '"ten Hacken, Elisa"'

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1. T-bet suppresses proliferation of malignant B cells in chronic lymphocytic leukemia

5. Dissecting Richter's Syndrome in a Multiplexed CRISPR-Based Mouse Model Reveals Key Changes in MYC, Interferon and BCR Signaling Underlying Transformation

6. B Cell-Restricted Depletion of Dnmt3a Activates Notch Signaling and Causes Chronic Lymphocytic Leukemia

7. IKZF3 Overexpression Phenocopies Gain-of-Function Mutation in Chronic Lymphocytic Leukemia

8. Expression of Sf3b1-K700E accelerates the Development of Chronic Lymphocytic Leukemia in a Del(13q) Murine Model

9. Multiplexed CRISPR In Vivo Editing of CLL Loss-of-Function Lesions Models Transformation of Chronic Lymphocytic Leukemia into Richter's Syndrome

10. RPS15 and TP53 Co-Mutation Drives B Cell Malignancy through Altered Translation and MYC Activation in a Murine Model

11. Interrogation of Individual CLL Loss-of-Function Lesions By CRISPR In Vivo Editing Reveals Common and Unique Pathway Alterations

12. Identification of Genotype-Specific Therapeutic Vulnerabilities By Comparative Dynamic BH3 Profiling Analysis of Human and Murine CLL

13. MCL-1 and PKA/AMPK Axis Fuel Venetoclax Resistance in Lymphoid Cancers

14. B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL

15. KZF-L162R Mutation Affects Splenic Mature B Cell Development and Alters Expression of Aiolos Target Genes

16. Integrated Genomic and Proteomic Analysis of Murine CLL-like Cells Reveals SF3B1 Mutation to Impact DNA Damage Response and BCR Signaling

18. HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment

19. IgM and IgD Receptors Differentially Contribute to CLL Survival and Chemokine Secretion: Implications for CLL Biology and Treatment

20. Identification of B Cell Receptor Antigens in the Chronic Lymphocytic Leukemia Microenvironment

21. Ibrutinib Targets Nurse-like Cells Supporting an Immunosuppressive Phenotype in Chronic Lymphocytic Leukemia

22. Correlation Between Clinical Responses and Immune Characteristics in Patients with Relapsed CLL Treated with Ofatumumab and Lenalidomide

24. Immunoglobulin Heavy Chain (IgH) Knockout Inhibits Proliferation of Pre-BCR+ B-Cell Acute Lymphoblastic Leukemia (B-ALL) Via a FOXO1 and MYC Dependent Mechanism

25. Targeting B-cell anergy in chronic lymphocytic leukemia

26. Targeting the LYN/HS1 signaling axis in chronic lymphocytic leukemia

27. Targeting the LYN/HS1 Signaling Axis in Chronic Lymphocytic Leukemia

28. Targeting B Cell Anergy in Chronic Lymphocytic Leukemia

29. HS1 has a central role in the trafficking and homing of leukemic B cells

30. Loss-of-function lesions impact B-cell development and fitness but are insufficient to drive CLL in mouse models.

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