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Start Over Author "Mecucci, Cristina" Publisher american society of hematology
57 results on '"Mecucci, Cristina"'

1. The Clinical Picture of the ERCC6L2 Disease - from Bone Marrow Failure to Acute Leukemia

Author

Hakkarainen, Marja, primary, Kaaja, Ilse, additional, Douglas, Suvi P. M., additional, Vulliamy, Thomas J, additional, Dokal, Inderjeet, additional, Soulier, Jean, additional, Larcher, Lise, additional, Peffault de Latour, Régis, additional, Leblanc, Thierry M, additional, Sicre de Fontbrune, Flore, additional, Siitonen, Timo, additional, Lohi, Olli, additional, Hellström-Lindberg, Eva, additional, Barbany, Gisela, additional, Tesi, Bianca, additional, Shimamura, Akiko, additional, Beier, Fabian, additional, Jackson, Sharon Rosalie, additional, Kuperman, Amir, additional, Falik Zaccai, Tzipora C., additional, Tamary, Hannah, additional, Mecucci, Cristina, additional, Capolsini, Ilaria, additional, Jahnukainen, Kirsi, additional, Salmenniemi, Urpu, additional, Niinimäki, Riitta, additional, Varilo, Teppo, additional, Kilpivaara, Outi, additional, and Wartiovaara-Kautto, Ulla, additional

Published
2023
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2. HLA-Matched Treg/Tcon Allogeneic Hematopoietic Cell Transplantation Is Safe and Ensures Remarkable Chronic GvHD/Leukemia Free Survival in High-Risk Leukemia Patients

Author

Pierini, Antonio, primary, Ruggeri, Loredana, additional, Saldi, Simonetta, additional, Tricarico, Sara, additional, Marzuttini, Francesca, additional, Viglione, Valerio, additional, Sembenico, Rebecca, additional, Zei, Tiziana, additional, Iacucci Ostini, Roberta, additional, Mancusi, Antonella, additional, Limongello, Roberto, additional, Minelli, Olivia, additional, Ingrosso, Gianluca, additional, Terenzi, Adelmo, additional, Martelli, Maria Paola, additional, Caniglia, Maurizio, additional, Mecucci, Cristina, additional, Velardi, Andrea, additional, Martelli, Massimo Fabrizio, additional, Aristei, Cynthia, additional, and Carotti, Alessandra, additional

Published
2022
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3. Orthogonal Proteogenomic Approaches Identify the Druggable PA2G4-MYC Axis in 3q26 AML

Author

Marchesini, Matteo, primary, Gherli, Andrea, additional, Simoncini, Elisa, additional, Montanaro, Anna, additional, Thongon, Natthakan, additional, Pagliaro, Luca, additional, Vento, Federica, additional, Moron Dalla Tor, Lucas, additional, Liverani, Chiara, additional, Zamponi, Raffaella, additional, Follini, Elena, additional, Cambò, Benedetta, additional, Lorusso, Bruno, additional, La Starza, Roberta, additional, Cuneo, Antonio, additional, Mecucci, Cristina, additional, Colla, Simona, additional, Quaini, Federico, additional, and Roti, Giovanni, additional

Published
2022
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4. Identification of the Atypical Protein Kinase WNK1 As a New Target in T-Cell Acute Lymphoblastic Leukemia

Author

Montanaro, Anna, primary, D'Antuono, Anna, additional, Moron Dalla Tor, Lucas, additional, Andrei, Pietro, additional, Ciringione, Alessia, additional, Cerretani, Elisa, additional, Vento, Federica, additional, Pagliaro, Luca, additional, Gherli, Andrea, additional, Lorusso, Bruno, additional, Simoncini, Elisa, additional, Zamponi, Raffaella, additional, Salvatori, Costanza, additional, Todaro, Giannalisa, additional, La Starza, Roberta, additional, Mecucci, Cristina, additional, Sammarelli, Gabriella, additional, Marchesini, Matteo, additional, and Roti, Giovanni, additional

Published
2022
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5. Guiding the global evolution of cytogenetic testing for hematologic malignancies

Author

Akkari, Yassmine M. N., primary, Baughn, Linda B., additional, Dubuc, Adrian M., additional, Smith, Adam C., additional, Mallo, Mar, additional, Dal Cin, Paola, additional, Diez Campelo, Maria, additional, Gallego, Marta S., additional, Granada Font, Isabel, additional, Haase, Detlef T., additional, Schlegelberger, Brigitte, additional, Slavutsky, Irma, additional, Mecucci, Cristina, additional, Levine, Ross L., additional, Hasserjian, Robert P., additional, Solé, Francesc, additional, Levy, Brynn, additional, and Xu, Xinjie, additional

Published
2022
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6. Association of unbalanced translocation der(1;7) with germline GATA2 mutations

Author

Kozyra, Emilia J., primary, Göhring, Gudrun, additional, Hickstein, Dennis D., additional, Calvo, Katherine R., additional, DiNardo, Courtney D., additional, Dworzak, Michael, additional, de Haas, Valerie, additional, Starý, Jan, additional, Hasle, Henrik, additional, Shimamura, Akiko, additional, Fleming, Mark D., additional, Inaba, Hiroto, additional, Lewis, Sara, additional, Hsu, Amy P., additional, Holland, Steven M., additional, Arnold, Danielle E., additional, Mecucci, Cristina, additional, Keel, Siobán B., additional, Bertuch, Alison A., additional, Tawana, Kiran, additional, Barzilai, Shlomit, additional, Hirabayashi, Shinsuke, additional, Onozawa, Masahiro, additional, Lei, Shaohua, additional, Alaiz, Helena, additional, Andrikovics, Hajnalka, additional, Betts, David, additional, Beverloo, Berna H., additional, Buechner, Jochen, additional, Čermák, Martin, additional, Cervera, José, additional, Haus, Olga, additional, Jahnukainen, Kirsi, additional, Manola, Kalliopi N., additional, Nebral, Karin, additional, Pasquali, Francesco, additional, Tchinda, Joelle, additional, Turkiewicz, Dominik, additional, Van Roy, Nadine, additional, Zemanova, Zuzana, additional, Pastor, Victor B., additional, Strahm, Brigitte, additional, Noellke, Peter, additional, Niemeyer, Charlotte M., additional, Schlegelberger, Brigitte, additional, Yoshimi, Ayami, additional, and Wlodarski, Marcin W., additional

Published
2021
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7. 14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T-lymphoid and myeloid immature acute leukemia

Author

Di Giacomo, Danika, La Starza, Roberta, Gorello, Paolo, Pellanera, Fabrizia, Kalender Atak, Zeynep; https://orcid.org/0000-0003-4761-8169, De Keersmaecker, Kim; https://orcid.org/0000-0002-7420-9531, Pierini, Valentina, Harrison, Christine J, Arniani, Silvia, Moretti, Martina, Testoni, Nicoletta, De Santis, Giovanna, Roti, Giovanni, Matteucci, Caterina; https://orcid.org/0000-0002-9553-4819, Bassan, Renato, Vandenberghe, Peter; https://orcid.org/0000-0003-4719-1935, Aerts, Stein, Cools, Jan; https://orcid.org/0000-0001-6626-5843, Bornhauser, Beat, Bourquin, Jean-Pierre, Piazza, Rocco; https://orcid.org/0000-0003-4198-9620, Mecucci, Cristina; https://orcid.org/0000-0002-1623-0148, Di Giacomo, Danika, La Starza, Roberta, Gorello, Paolo, Pellanera, Fabrizia, Kalender Atak, Zeynep; https://orcid.org/0000-0003-4761-8169, De Keersmaecker, Kim; https://orcid.org/0000-0002-7420-9531, Pierini, Valentina, Harrison, Christine J, Arniani, Silvia, Moretti, Martina, Testoni, Nicoletta, De Santis, Giovanna, Roti, Giovanni, Matteucci, Caterina; https://orcid.org/0000-0002-9553-4819, Bassan, Renato, Vandenberghe, Peter; https://orcid.org/0000-0003-4719-1935, Aerts, Stein, Cools, Jan; https://orcid.org/0000-0001-6626-5843, Bornhauser, Beat, Bourquin, Jean-Pierre, Piazza, Rocco; https://orcid.org/0000-0003-4198-9620, and Mecucci, Cristina; https://orcid.org/0000-0002-1623-0148

Abstract

Acute leukemias (ALs) of ambiguous lineage are a heterogeneous group of high-risk leukemias characterized by coexpression of myeloid and lymphoid markers. In this study, we identified a distinct subgroup of immature acute leukemias characterized by a broadly variable phenotype, covering acute myeloid leukemia (AML, M0 or M1), T/myeloid mixed-phenotype acute leukemia (T/M MPAL), and early T-cell precursor acute lymphoblastic leukemia (ETP-ALL). Rearrangements at 14q32/BCL11B are the cytogenetic hallmark of this entity. In our screening of 915 hematological malignancies, there were 202 AML and 333 T-cell acute lymphoblastic leukemias (T-ALL: 58, ETP; 178, non-ETP; 8, T/M MPAL; 89, not otherwise specified). We identified 20 cases of immature leukemias (4% of AML and 3.6% of T-ALL), harboring 4 types of 14q32/BCL11B translocations: t(2,14)(q22.3;q32) (n = 7), t(6;14)(q25.3;q32) (n = 9), t(7;14)(q21.2;q32) (n = 2), and t(8;14)(q24.2;q32) (n = 2). The t(2;14) produced a ZEB2-BCL11B fusion transcript, whereas the other 3 rearrangements displaced transcriptionally active enhancer sequences close to BCL11B without producing fusion genes. All translocations resulted in the activation of BCL11B, a regulator of T-cell differentiation associated with transcriptional corepressor complexes in mammalian cells. The expression of BCL11B behaved as a disease biomarker that was present at diagnosis, but not in remission. Deregulation of BCL11B co-occurred with variants at FLT3 and at epigenetic modulators, most frequently the DNMT3A, TET2, and/or WT1 genes. Transcriptome analysis identified a specific expression signature, with significant downregulation of BCL11B targets, and clearly separating BCL11B AL from AML, T-ALL, and ETP-ALL. Remarkably, an ex vivo drug-sensitivity profile identified a panel of compounds with effective antileukemic activity.

Published
2021

8. 14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T and myeloid immature acute leukemia

Author

Di Giacomo, Danika, primary, La Starza, Roberta, additional, Gorello, Paolo, additional, Pellanera, Fabrizia, additional, Kalender Atak, Zeynep, additional, De Keersmaecker, Kim, additional, Pierini, Valentina, additional, Harrison, Christine J, additional, Arniani, Silvia, additional, Moretti, Martina, additional, Testoni, Nicoletta, additional, De Santis, Giovanna, additional, Roti, Giovanni, additional, Matteucci, Caterina, additional, Bassan, Renato, additional, Vandenberghe, Peter, additional, Aerts, Stein, additional, Cools, Jan, additional, Bornhauser, Beat, additional, Bourquin, Jean-Pierre, additional, Piazza, Rocco, additional, and Mecucci, Cristina, additional

Published
2021
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9. Haploidentical age-adapted myeloablative transplant and regulatory and effector T cells for acute myeloid leukemia

Author

Pierini, Antonio, primary, Ruggeri, Loredana, additional, Carotti, Alessandra, additional, Falzetti, Franca, additional, Saldi, Simonetta, additional, Terenzi, Adelmo, additional, Zucchetti, Claudio, additional, Ingrosso, Gianluca, additional, Zei, Tiziana, additional, Iacucci Ostini, Roberta, additional, Piccinelli, Sara, additional, Bonato, Samanta, additional, Tricarico, Sara, additional, Mancusi, Antonella, additional, Ciardelli, Sara, additional, Limongello, Roberto, additional, Merluzzi, Mara, additional, Di Ianni, Mauro, additional, Tognellini, Rita, additional, Minelli, Olivia, additional, Mecucci, Cristina, additional, Martelli, Maria Paola, additional, Falini, Brunangelo, additional, Martelli, Massimo Fabrizio, additional, Aristei, Cynthia, additional, and Velardi, Andrea, additional

Published
2021
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10. ETNK1 Mutations in Atypical Chronic Myeloid Leukemia Induce a Mutator Phenotype That Can be Reverted with Phosphoethanolamine

Author

Fontana, Diletta, primary, Mauri, Mario, additional, Renso, Rossella, additional, Docci, Mattia, additional, Crespiatico, Ilaria, additional, Røst, Lisa M, additional, Jang, Mi, additional, Niro, Antonio, additional, D'Aliberti, Deborah, additional, Massimino, Luca, additional, Bertagna, Mayla, additional, Zambrotta, Giovanni, additional, Bossi, Mario, additional, Citterio, Stefania, additional, Crescenzi, Barbara, additional, Fanelli, Francesca, additional, Cassina, Valeria, additional, Corti, Roberta, additional, Salerno, Domenico, additional, Nardo, Luca, additional, Chinello, Clizia, additional, Mantegazza, Francesco, additional, Mecucci, Cristina, additional, Magni, Fulvio, additional, Cavaletti, Guido, additional, Bruheim, Per, additional, Rea, Delphine, additional, Larsen, Steen, additional, Piazza, Rocco, additional, and Gambacorti-Passerini, Carlo, additional

Published
2020
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11. Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Author

De Smedt, Renate, primary, Morscio, Julie, primary, Reunes, Lindy, primary, Roels, Juliette, primary, Bardelli, Valentina, primary, Lintermans, Beatrice, primary, Van Loocke, Wouter, primary, Almeida, Afonso, primary, Cheung, Laurence C., primary, Kotecha, Rishi S., primary, Mansour, Marc R., primary, Uyttebroeck, Anne, primary, Vandenberghe, Peter, primary, La Starza, Roberta, primary, Mecucci, Cristina, primary, Lammens, Tim, primary, Van Roy, Nadine, primary, De Moerloose, Barbara, primary, Barata, João T., primary, Taghon, Tom, primary, Goossens, Steven, primary, and Van Vlierberghe, Pieter, primary

Published
2020
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12. Haploidentical Transplantation with Regulatory and Conventional T Cells Improves Outcome of Patients Affected By Acute Myeloid Leukemia with Complex Karyotype and/or Monosomy 7/Del(7q)

Author

Pierini, Antonio, primary, Marra, Andrea, additional, Carotti, Alessandra, additional, Ruggeri, Loredana, additional, Terenzi, Adelmo, additional, Falzetti, Franca, additional, Piccinelli, Sara, additional, Cardinali, Valeria, additional, Mancusi, Antonella, additional, Tardioli, Cecilia, additional, Felicini, Rita, additional, Lucia, Amico, additional, Casarola, Genni, additional, Tricarico, Sara, additional, Bonato, Samanta, additional, Paradiso, Matteo, additional, Griselli, Mario, additional, Crescenzi, Barbara, additional, La Starza, Roberta, additional, Mecucci, Cristina, additional, Falini, Brunangelo, additional, Martelli, Massimo Fabrizio, additional, Martelli, Maria Paola, additional, and Velardi, Andrea, additional

Published
2018
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13. Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB

Author

Brown, Anna L., primary, Armstrong, Mark, additional, Lawrence, David, additional, Wang, Paul, additional, Arts, Peer, additional, Duployez, Nicolas, additional, Churpek, Jane, additional, Tawana, Kiran, additional, Degelman, Erin, additional, Natsoulis, Georges, additional, Guzman, Monica L., additional, Patnaik, Mrinal M., additional, Shimamura, Akiko, additional, Cantor, Alan B., additional, Ripperger, Tim, additional, Schlegelberger, Brigitte, additional, Steinemann, Doris, additional, DiNardo, Courtney D., additional, Mecucci, Cristina, additional, Velloso, Elvira DRP, additional, Santos, Fabio PS, additional, Silva, Marcela CA, additional, Borate, Uma, additional, McWeeney, Shannon K., additional, Nalepa, Grzegorz, additional, Ragg, Susanne, additional, Kwon, Erika Mijin, additional, Agarwal, Anupriya, additional, Langabeer, Stephen, additional, Klco, Jeffery M., additional, Yang, Jun J., additional, Forsyth, Cecily, additional, Mapp, Sally, additional, Mar Fan, Helen, additional, Rawlings, Lesley, additional, Susman, Rachel, additional, Morgan, Sue, additional, Wei, Andrew H, additional, Dokal, Inderjeet, additional, Vulliamy, Tom, additional, Hiwase, Devendra K, additional, Singhal, Deepak, additional, Branford, Susan, additional, Papaemmanuil, Elli, additional, Soulier, Jean, additional, Fröhling, Stefan, additional, Kramer, Alwin, additional, Sauvageau, Guy, additional, Morgan, Neil, additional, Owen, Carolyn, additional, Bödör, Csaba, additional, Fitzgibbon, Jude, additional, Rienhoff, Hugh Y., additional, Kurokawa, Mineo, additional, Godley, Lucy, additional, Preudhomme, Claude, additional, Liu, Paul P, additional, Poplawski, Nicola, additional, Hahn, Christopher N., additional, and Scott, Hamish S., additional

Published
2018
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14. Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma

Author

Tiacci, Enrico, primary, Ladewig, Erik, additional, Schiavoni, Gianluca, additional, Penson, Alex, additional, Fortini, Elisabetta, additional, Pettirossi, Valentina, additional, Wang, Yuchun, additional, Rosseto, Ariele, additional, Venanzi, Alessandra, additional, Vlasevska, Sofija, additional, Pacini, Roberta, additional, Piattoni, Simonetta, additional, Tabarrini, Alessia, additional, Pucciarini, Alessandra, additional, Bigerna, Barbara, additional, Santi, Alessia, additional, Gianni, Alessandro M., additional, Viviani, Simonetta, additional, Cabras, Antonello, additional, Ascani, Stefano, additional, Crescenzi, Barbara, additional, Mecucci, Cristina, additional, Pasqualucci, Laura, additional, Rabadan, Raul, additional, and Falini, Brunangelo, additional

Published
2018
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15. The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling

Author

Li, Jin, primary, Riedt, Tamara, additional, Goossens, Steven, additional, Carrillo García, Carmen, additional, Szczepanski, Sabrina, additional, Brandes, Maria, additional, Pieters, Tim, additional, Dobrosch, Linne, additional, Gütgemann, Ines, additional, Farla, Natalie, additional, Radaelli, Enrico, additional, Hulpiau, Paco, additional, Mallela, Nikhil, additional, Fröhlich, Holger, additional, La Starza, Roberta, additional, Matteucci, Caterina, additional, Chen, Tong, additional, Brossart, Peter, additional, Mecucci, Cristina, additional, Huylebroeck, Danny, additional, Haigh, Jody J., additional, and Janzen, Viktor, additional

Published
2017
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16. New Recurrently Mutated Genes in Classical Hodgkin Lymphoma Revealed By Whole-Exome Sequencing of Microdissected Tumor Cells

Author

Tiacci#, Enrico, primary, Penson#, Alexander, additional, Schiavoni#, Gianluca, additional, Ladewig#, Erik, additional, Fortini#, Elisabetta, additional, Wang, Yuchun, additional, Spanhol-Rosseto, Ariele, additional, Venanzi, Alessandra, additional, Gianni, Alessandro M., additional, Viviani, Simonetta, additional, Cabras, Antonello, additional, Crescenzi, Barbara, additional, Mecucci, Cristina, additional, Pasqualucci°, Laura, additional, Rabadan°, Raul, additional, and Falini°, Brunangelo, additional

Published
2016
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17. Haploinsufficiency for NR3C1, the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms

Author

Emadali, Anouk, primary, Hoghoughi, Neda, additional, Duley, Samuel, additional, Hajmirza, Azadeh, additional, Verhoeyen, Els, additional, Cosset, Francois-Loic, additional, Bertrand, Philippe, additional, Roumier, Christophe, additional, Roggy, Anne, additional, Suchaud-Martin, Céline, additional, Chauvet, Martine, additional, Bertrand, Sarah, additional, Hamaidia, Sieme, additional, Rousseaux, Sophie, additional, Josserand, Véronique, additional, Charles, Julie, additional, Templier, Isabelle, additional, Maeda, Takahiro, additional, Bruder-Costa, Juliana, additional, Chaperot, Laurence, additional, Plumas, Joel, additional, Jacob, Marie-Christine, additional, Bonnefoix, Thierry, additional, Park, Sophie, additional, Gressin, Remy, additional, Tensen, Cornelis P., additional, Mecucci, Cristina, additional, Macintyre, Elizabeth, additional, Leroux, Dominique, additional, Brambilla, Elisabeth, additional, Nguyen-Khac, Florence, additional, Luquet, Isabelle, additional, Penther, Dominique, additional, Bastard, Christian, additional, Jardin, Fabrice, additional, Lefebvre, Christine, additional, Garnache, Francine, additional, and Callanan, Mary B., additional

Published
2016
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18. Use of Lenalidomide in DEL(5q) MDS. a National AIFA (Agenzia Italiana del Farmaco) Registry Study

Author

Arcioni, Francesco, primary, Roncadori, Andrea, additional, Di Battista, Valeria, additional, Alimena, Giuliana, additional, Pane, Fabrizio, additional, Rossi, Giuseppe, additional, Buccisano, Francesco, additional, D'Emilio, Anna, additional, Di Renzo, Nicola, additional, Leoni, Pietro, additional, Caocci, Giovanni, additional, Rambaldi, Alessandro, additional, Avanzini, Paolo, additional, Visani, Giuseppe, additional, Tura, Sante, additional, Covezzoli, Anna, additional, and Mecucci, Cristina, additional

Published
2015
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19. Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations

Author

La Starza, R, Borga, C, Barba, G, Pierini, V, Schwab, C, Matteucci, C, Lema Fernandez, A, Leszl, A, Cazzaniga, G, Chiaretti, S, Basso, G, Harrison, C, Te Kronnie, G, Mecucci, C, La Starza, Roberta, Borga, Chiara, Barba, Gianluca, Pierini, Valentina, Schwab, Claire, Matteucci, Caterina, Lema Fernandez, Anair G., Leszl, Anna, Cazzaniga, Giovanni, Chiaretti, Sabina, Basso, Giuseppe, Harrison, Christine J., Te Kronnie, Geertruy, Mecucci, Cristina, La Starza, R, Borga, C, Barba, G, Pierini, V, Schwab, C, Matteucci, C, Lema Fernandez, A, Leszl, A, Cazzaniga, G, Chiaretti, S, Basso, G, Harrison, C, Te Kronnie, G, Mecucci, C, La Starza, Roberta, Borga, Chiara, Barba, Gianluca, Pierini, Valentina, Schwab, Claire, Matteucci, Caterina, Lema Fernandez, Anair G., Leszl, Anna, Cazzaniga, Giovanni, Chiaretti, Sabina, Basso, Giuseppe, Harrison, Christine J., Te Kronnie, Geertruy, and Mecucci, Cristina

Abstract

MYC translocations represent a genetic subtype of T-lineage acute lymphoblastic leukemia (T-ALL), which occurs at an incidence of ∼6%, assessed within a cohort of 196 T-ALL patients (64 adults and 132 children). The translocations were of 2 types; those rearranged with the T-cell receptor loci and those with other partners. MYCtranslocations were significantly associated with the TAL/LMO subtype of T-ALL (P 5 .018) and trisomies 6 (P < .001) and 7 (P < .001). Within the TAL/LMO subtype, gene expression profiling identified 148 differentially expressed genes between patients with and without MYC translocations; specifically, 77 were upregulated and 71 downregulated in those with MYC translocations. The poor prognostic marker, CD44, was among the upregulated genes. MYC translocations occurred as secondary abnormalities, present in subclones in one-half of the cases. Longitudinal studies indicated an association with induction failure and relapse.

Published
2014

20. NUP98 Fusion Proteins Are Recurrent Aberrancies in Childhood Acute Myeloid Leukemia: A Report from the AIEOP AML-2001-02 Study Group

Author

Bisio, Valeria, primary, Pigazzi, Martina, additional, Manara, Elena, additional, Masetti, Riccardo, additional, Togni, Marco, additional, Astolfi, Annalisa, additional, Mecucci, Cristina, additional, Zappavigna, Vincenzo, additional, Salsi, Valentina, additional, Merli, Pietro, additional, Rizzari, Carmelo, additional, Fagioli, Franca, additional, Locatelli, Franco, additional, and Basso, Giuseppe, additional

Published
2014
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21. Targeted Re-Sequencing Analysis of 31 Genes Commonly Mutated in Myeloid Disorders in Serial Samples from Myelodysplastic Syndrome Patients with Disease Progression

Author

Pellagatti, Andrea, primary, Di Genua, Cristina, additional, Roy, Swagata, additional, Burns, Adam, additional, McGraw, Kathy L, additional, Larrayoz, Maria José, additional, Fernandez-Mercado, Marta, additional, Valletta, Simona, additional, Mason, Joanne, additional, Killick, Sally, additional, Mecucci, Cristina, additional, Calasanz, Maria José, additional, List, Alan F., additional, Schuh, Anna, additional, and Boultwood, Jacqueline, additional

Published
2014
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22. TERT Gene Promoter Mutations In Myelodysplastic Syndromes (MDS)

Author

Matteucci, Caterina, primary, Iannotti, Tamara, additional, Brandimarte, Lucia, additional, Nofrini, Valeria, additional, Barba, Gianluca, additional, Sgura, Antonella, additional, Berardinelli, Francesco, additional, Nozza, Filomena, additional, Di Battista, Valeria, additional, and Mecucci, Cristina, additional

Published
2013
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23. Therapy-Related Myeloid Neoplasms: Report Of The Italian Network On Secondary Leukemias

Author

Fianchi, Luana, primary, Voso, Maria Teresa, additional, Candoni, Anna, additional, Gaidano, Gianluca, additional, Criscuolo, Marianna, additional, Specchia, Giorgina, additional, Pogliani, Enrico Maria, additional, Monarca, Bruno, additional, Maurillo, Luca, additional, Mecucci, Cristina, additional, Breccia, Massimo, additional, Aversa, Franco, additional, Musto, Pellegrino, additional, Rondoni, Michela, additional, Niscola, Pasquale, additional, Fozza, Claudio, additional, Invernizzi, Rosangela, additional, Spadea, Antonio, additional, Fenu, Susanna, additional, Buda, Gabriele, additional, Gobbi, Marco, additional, Santini, Valeria, additional, Mancini, Stefano, additional, Morra, Enrica, additional, Pagano, Livio, additional, and Leone, Giuseppe, additional

Published
2013
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24. New MLLT10 gene recombinations in pediatric T-acute lymphoblastic leukemia

Author

Brandimarte, Lucia, primary, Pierini, Valentina, additional, Di Giacomo, Danika, additional, Borga, Chiara, additional, Nozza, Filomena, additional, Gorello, Paolo, additional, Giordan, Marco, additional, Cazzaniga, Giovanni, additional, te Kronnie, Geertruy, additional, La Starza, Roberta, additional, and Mecucci, Cristina, additional

Published
2013
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26. Activation of the mTOR Signaling Pathway by L-Leucine in RPS14-Deficient Erythroid Cells

Author

Yip, Bon Ham, primary, Vuppusetty, Chaitanya, additional, Pellagatti, Andrea, additional, Giagounidis, Aristoteles, additional, Germing, Ulrich, additional, Lamikanra, Abigail A, additional, Roberts, David J, additional, Fernandez-Mercado, Marta, additional, McDonald, Emma-Jane, additional, Mecucci, Cristina, additional, Killick, Sally, additional, Wainscoat, James S, additional, and Boultwood, Jacqueline, additional

Published
2012
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27. Lenalidomide in Myelodysplastic Syndromes with 5q Deletion. Results From the Italian National Cancer Registry

Author

Mecucci, Cristina, primary, Roncadori, Andrea, additional, La Starza, Roberta, additional, Arcioni, Francesco, additional, Levis, Alessandro, additional, Santini, Valeria, additional, Alimena, Giuliana, additional, Pane, Fabrizio, additional, Rossi, Giuseppe, additional, Cantonetti, Maria, additional, D'Emilio, Anna, additional, Di Renzo, Nicola, additional, Leoni, Pietro, additional, Caocci, Giovanni, additional, Rambaldi, Alessandro, additional, Avanzini, Paolo, additional, Visani, Giuseppe, additional, Tura, Sante, additional, and Covezzoli, Anna, additional

Published
2012
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28. CI-FISH, GEP, and SNPs Correlate Genomic Categories with Risk Stratification in Children with T-ALL.

Author

la Starza, Roberta, primary, Lettieri, Antonella, additional, Pierini, Valentina, additional, Matteucci, Caterina, additional, Nofrini, Valeria, additional, Gorello, Paolo, additional, Songia, Simona, additional, Crescenzi, Barbara, additional, te Kronnie, Geertruy, additional, Giordan, Marco, additional, Leszl, Anna, additional, Valsecchi, Maria Grazia, additional, Aversa, Franco, additional, Basso, Giuseppe, additional, Biondi, Andrea, additional, Conter, Valentino, additional, Cazzaniga, Giovanni, additional, and Mecucci, Cristina, additional

Published
2012
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30. A Simple Clinical Prognostic Scoring System for Newly Diagnosed Cytogenetically Normal Acute Myeloid Leukemia: a Retrospective Analysis on 530 Patients

Author

Malagola, Michele, primary, Skert, Crisitina, additional, Vignetti, Marco, additional, Piciocchi, Alfonso, additional, Martinelli, Giovanni, additional, Mecucci, Cristina, additional, Testoni, Nicoletta, additional, Iacobucci, Ilaria, additional, Clavio, Marino, additional, Gobbi, Marco, additional, Anna, Candoni, additional, Damiani, Daniela, additional, Bocchia, Monica, additional, Lauria, Francesco, additional, Zaccaria, Alfonso, additional, Mazza, Patrizio, additional, Visani, Giuseppe, additional, Annalisa, Peli, additional, Mancini, Marco, additional, Foà, Robin, additional, Martelli, Massimo, additional, Cantore, Nicola, additional, Raimondo, Francesco Di, additional, Petrini, Mario, additional, de Fabritiis, Paolo, additional, Fioritoni, Giuseppe, additional, Nobile, Francesco, additional, Fabbiano, Francesco, additional, Specchia, Giorgina, additional, Baccarani, Michele, additional, Coco, Francesco Lo, additional, Amadori, Sergio, additional, Mandelli, Franco, additional, and Russo, Domenico, additional

Published
2010
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31. AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features

Author

Haferlach, Claudia, primary, Mecucci, Cristina, additional, Schnittger, Susanne, additional, Kohlmann, Alexander, additional, Mancini, Marco, additional, Cuneo, Antonio, additional, Testoni, Nicoletta, additional, Rege-Cambrin, Giovanna, additional, Santucci, Antonella, additional, Vignetti, Marco, additional, Fazi, Paola, additional, Martelli, Maria Paola, additional, Haferlach, Torsten, additional, and Falini, Brunangelo, additional

Published
2009
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33. Myeloid Cell Differentiation Arrest by Mir-125b-1 in Myelodysplasic Syndrome and Acute Myeloid Leukemia with the T(2;11)(p21;q23) Translocation

Author

Bousquet, Marina, primary, Quelen, Cathy, primary, Rosati, Roberto, primary, Mas, Véronique Mansat-De, primary, Bastard, Christian, primary, Lippert, Eric, primary, Talmant, Pascaline, primary, Lafage-Pochitaloff, Marina, primary, Leroux, Dominique, primary, Gervais, Carine, primary, Viguie, Franck, primary, Lai, Jean-Luc, primary, Terre, Christine, primary, Delsol, Georges, primary, Dastugue, Nicole, primary, Mecucci, Cristina, primary, and Brousset, Pierre, primary

Published
2008
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36. Comparison of Cytogenetics and Interphase Fluorescence In Situ Hybridization in Newly Diagnosed Ph+ Chronic Myeloid Leukemia Patients Treated with Imatinib Mesylate. A Study by the GIMEMA Working Party on CML. On Behalf of GWP on CML.

Author

Testoni, Nicoletta, primary, Luatti, Simona, primary, Nicci, Chiara, primary, Montanari, Elena, primary, Marzocchi, Giulia, primary, Specchia, Giorgina, primary, Mancini, Marco, primary, Abruzzese, Elisabetta, primary, Rege-Cambrin, Giovanna, primary, Cuneo, Antonio, primary, Kerim, Simonetta, primary, Giussani, Ursula, primary, Bernasconi, Paolo, primary, Mecucci, Cristina, primary, Zaccaria, Alfonso, primary, Discepoli, Giancarlo, primary, Martinelli, Giovanni, primary, Rosti, Gianantonio, primary, and Baccarani, Michele, primary

Published
2005
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37. Imatinib Mesylate Can Induce Molecular Complete Remission in Idiopathic Hypereosinophilic Syndrome (HES). A Phase II Multicentric Italian Clinical Trial.

Author

Martinelli, Giovanni, primary, Cilloni, Daniela, primary, Rondoni, Michela, primary, Messa, Francesca, primary, Ottaviani, Emanuela, primary, Gottardi, Enrico, primary, Piccaluga, Pier Paolo, primary, Malagola, Michele, primary, Soverini, Simona, primary, Merante, Serena, primary, Alimena, Giuliana, primary, Bosi, Costanza, primary, De Vivo, Antonio, primary, Rosti, Gianantonio, primary, Giugliano, Emilia, primary, Pane, Fabrizio, primary, Izzo, Barbara, primary, Testoni, Nicoletta, primary, Paolini, Stefania, primary, Rancati, Francesca, primary, Bassan, Renato, primary, Mecucci, Cristina, primary, Baccarani, Michele, primary, and Saglio, Giuseppe, primary

Published
2005
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38. Mechanism of Altered Nucleo-Cytoplasmic Traffic of Nucleophosmin in Acute Myelogenous Leukemia Carrying Exon-12 NPM Mutations (NPMc+ AML).

Author

Falini, Brunangelo, primary, Bolli, Niccolo, additional, Shan, Jing, additional, Martelli, Maria Paola, additional, Nicoletti, Ildo, additional, Liso, Arcangelo, additional, Pasqualucci, Laura, additional, Rosati, Roberto, additional, Roti, Giovanni, additional, Diverio, Daniela, additional, Mannucci, Roberta, additional, Cazzaniga, Giovanni, additional, Biondi, Andrea, additional, Saglio, Giuseppe, additional, Pane, Fabrizio, additional, Lo-Coco, Francesco, additional, Pelicci, Pier-Giuseppe, additional, Martelli, Massimo F., additional, Gu, Wei, additional, and Mecucci, Cristina, additional

Published
2005
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39. Quantitative Detection of NPM1 Mutations as Marker of Minimal Residual Disease (MRD) in the Large Majority of AML with Normal Karyotype.

Author

Saglio, Giuseppe, primary, Gorello, Paolo, additional, Cazzaniga, Giovanni, additional, Gottardi, Enrico, additional, Dell’Oro, Maria Grazia, additional, Rosati, Roberto, additional, Roti, Giovanni, additional, Alberti, Federica, additional, Diverio, Daniela, additional, Martelli, Massimo Fabrizio, additional, Lo Coco, Francesco, additional, Biondi, Andrea, additional, Falini, Brunangelo, additional, and Mecucci, Cristina, additional

Published
2005
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40. Detection of the NUP214-ABL Rearrangement in T-ALL by High-Density Oligonucleotide Arrays: Evidence of the Value of This Approach in the Identification of Gene Amplifications.

Author

Chiaretti, Sabina, primary, Tavolaro, Simona, primary, Ghia, Emanuela, primary, Ariola, Cristina, primary, Matteucci, Caterina, primary, Maggio, Roberta, primary, Vitale, Antonella, primary, Ritz, Jerome, primary, Mecucci, Cristina, primary, Guarini, Anna, primary, and Foà, Robert, primary

Published
2005
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41. Exon-12 Nucleophosmin (NPM) Mutation and Aberrant Cytoplasmic Expression of NPM Protein in Leukemia Cell Line OCI-AML3.

Author

Quentmeier, Hilmar, primary, Martelli, Maria P., primary, Dirks, Wilhelm G., primary, Bolli, Niccolo, primary, Liso, Arcangelo, primary, MacLeod, Roderick A.F., primary, Nicoletti, Ildo, primary, Mannucci, Roberta, primary, Pucciarini, Alessandra, primary, Bigerna, Barbara, primary, Martelli, Massimo F., primary, Mecucci, Cristina, primary, Drexler, Hans G., primary, and Falini, Brunangelo, primary

Published
2005
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42. Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype

Author

Cazzaniga, Giovanni, primary, Dell'Oro, Maria Grazia, additional, Mecucci, Cristina, additional, Giarin, Emanuela, additional, Masetti, Riccardo, additional, Rossi, Vincenzo, additional, Locatelli, Franco, additional, Martelli, Massimo F., additional, Basso, Giuseppe, additional, Pession, Andrea, additional, Biondi, Andrea, additional, and Falini, Brunangelo, additional

Published
2005
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43. Idiopathic Hypereosinophilic Syndrome (HES) with FIP1L1-PDGFRA Rearrangement Can Be Effectively Treated with Imatinib.

Author

Martinelli, Giovanni, primary, Cilloni, Daniela, additional, Ottaviani, Emanuela, additional, Malagola, Michele, additional, Messa, Francesca, additional, Rondoni, Michela, additional, Bosi, Costanza, additional, Gottardi, Enrico, additional, Rosti, Gianantonio, additional, Ricci, Paolo, additional, Gaitani, Stavroula, additional, Pane, Fabrizio, additional, Testoni, Nicoletta, additional, Mecucci, Cristina, additional, Soverini, Simona, additional, Piccaluga, Pier Paolo, additional, Amabile, Marilina, additional, Tiribelli, Mario, additional, Zaccaria, Alfonso, additional, Grafone, Tiziana, additional, De Vivo, Antonello, additional, Pileri, Stefano, additional, Fattori, Pierpaolo, additional, Bocchia, Monica, additional, Serra, Anna, additional, Maurillo, Luca, additional, Fanin, Renato, additional, Cross, Nicholas C.P., additional, Merante, Serena, additional, Cazzola, Mario, additional, Alimena, Giuliana, additional, Frassoni, Francesco, additional, Galieni, Piero, additional, Russo, Domenico, additional, Gobbi, Marco, additional, Gugliotta, Luigi, additional, Lauria, Francesco, additional, Mazza, Patrizio, additional, Ferrara, Felicetto, additional, Gherlinzoni, Filippo, additional, Leoni, Pietro, additional, Musto, Pellegrino, additional, Baccarani, Michele, additional, and Saglio, Giuseppe, additional

Published
2004
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46. European Multicenter Experience on Idiopathic Hypereosinophilic Syndrome (HES) with FIP1L1-PDGFRA Rearrangement treated with Imatinib.

Author

Martinelli, Giovanni, primary, Apperley, Jane, additional, Reiter, Andreas, additional, Cross, Nicholas P., additional, Cilloni, Daniela, additional, Grimwade, David, additional, Hochhaus, Andreas, additional, Ottaviani, Emanuela, additional, Cools, Jan, additional, Prin, Lionel, additional, Malagola, Michele, additional, Walz, C, additional, Preudhomme, Claude, additional, Messa, Francesca, additional, Rondoni, Michela, additional, Gottardi, Enrico, additional, Rosti, Gianantonio, additional, Mecucci, Cristina, additional, Pane, Fabrizio, additional, Testoni, Nicoletta, additional, Soverini, Simona, additional, Merante, Serena, additional, Alimena, Giuliana, additional, Baccarani, Michele, additional, Hehlmann, Rudiger, additional, Aventin, Anna, additional, Sureda, Anna, additional, Gomez, Jose-Roman, additional, Duyster, Justus, additional, Verhoef, Gregor, additional, and Saglio, Giuseppe, additional

Published
2004
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49. H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor β gene in atypical chronic myeloid leukemia with t(5;10)(q33;q22)

Author

Schwaller, Juerg, primary, Anastasiadou, Ema, additional, Cain, Danielle, additional, Kutok, Jeff, additional, Wojiski, Sarah, additional, Williams, Ifor R., additional, LaStarza, Roberta, additional, Crescenzi, Barbara, additional, Sternberg, David W., additional, Andreasson, Patrick, additional, Schiavo, Roberta, additional, Siena, Salvatore, additional, Mecucci, Cristina, additional, and Gilliland, D. Gary, additional

Published
2001
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