37 results on '"Denis, Cécile V."'
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2. A hemophilia A mouse model for the in vivo assessment of emicizumab function
3. Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia
4. Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor
5. The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction
6. A mutation of the human EPHB2 gene leads to a major platelet functional defect
7. A factor VIII–nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation
8. Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets
9. VWF clearance: it’s glycomplicated
10. Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?
11. Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions
12. Macrophage receptor SR-AI is crucial to maintain normal plasma levels of coagulation factor X
13. Impaired platelet activation and cAMP homeostasis in MRP4-deficient mice
14. von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends
15. Hemostatic disorders in a JAK2V617F-driven mouse model of myeloproliferative neoplasm
16. Expression of a structurally constrained von Willebrand factor variant triggers acute thrombotic thrombocytopenic purpura in mice
17. GpIbα-VWF blockade restores vessel patency by dissolving platelet aggregates formed under very high shear rate in mice
18. Platelet von Willebrand factor: sweet resistance
19. Accelerated uptake of VWF/platelet complexes in macrophages contributes to VWD type 2B–associated thrombocytopenia
20. Mutations in the A3 domain of Von Willebrand factor inducing combined qualitative and quantitative defects in the protein
21. Determinants of von Willebrand Factor Function
22. A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor
23. Macrophage LRP1 contributes to the clearance of von Willebrand factor
24. Siglecs as Novel Cellular Partners for Von Willebrand Factor
25. Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2B
26. Macrophages contribute to the cellular uptake of von Willebrand factor and factor VIII in vivo
27. Altered thrombus formation in von Willebrand factor–deficient mice expressing von Willebrand factor variants with defective binding to collagen or GPIIbIIIa
28. Pas de deux between VWF and ADAMTS13
29. Correction of the bleeding time in von Willebrand factor (VWF)–deficient mice using murine VWF
30. O-Linked Glycosylation with Sialylated T-Antigen: A Novel Carbohydrate Determinant of von Willebrand Factor Antigen Levels.
31. Variations in glycosylation of von Willebrand factor with O-linked sialylated T antigen are associated with its plasma levels
32. Von Willebrand factor C1C2 domain is involved in platelet adhesion to polymerized fibrin at high shear rate
33. Localized reduction of atherosclerosis in von Willebrand factor–deficient mice
34. Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models
35. Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins
36. Hemostatic disorders in a JAK2V617F -driven mouse model of myeloproliferative neoplasm.
37. Mutations in the A3 domain of Von Willebrand factor inducing combined qualitative and quantitative defects in the protein.
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