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1. The effect of topically applied fluorescein on fluorescent monoclonal antibodies in the diagnosis of chlamydial conjunctivitis.

Author

Vrabec MP and McCanna PJ

Subjects
Administration, Topical, Antibodies, Monoclonal, Chlamydia trachomatis, Clinical Trials as Topic, Fluorescent Antibody Technique, Humans, Chlamydia Infections diagnosis, Conjunctivitis diagnosis, Fluoresceins
Abstract

Fluorescein-conjugated monoclonal antibodies have now been developed for use in the diagnosis of chlamydial conjunctivitis. This article discusses a clinical trial involving the use of such antibodies. We found that topical application of fluorescein before obtaining a specimen did not result in a statistically significant rate of false positives in a control group of patients.

Published
1988

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