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Start Over Author "Keiko Kawaguchi" Publisher american society of clinical oncology (asco)
1 results on '"Keiko Kawaguchi"'

1. Phase I expansion of S-222611, a reversible inhibitor of EGFR and HER2, in advanced solid tumors, including patients with brain metastases

Author

Nicola Cresti, K Donaldson, Ruth Plummer, James Spicer, Linda Hogarth, Keiko Kawaguchi, Debashis Sarker, Javier Garcia-Corbacho, J Posner, Sanjeev Deva, Duncan I. Jodrell, A Arimura, Eugene P. Frenkel, and Richard D. Baird

Subjects
Cancer Research, Oncology, ErbB, medicine.drug_class, business.industry, Phase (matter), Cancer research, medicine, skin and connective tissue diseases, business, neoplasms, Tyrosine-kinase inhibitor
Abstract

2511 Background: S-222611 is an oral, reversible ErbB tyrosine kinase inhibitor of EGFR and HER2 with potent pre-clinical activity. MTD was not reached during dose-escalation, even at the maximum d...

Published
2015

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