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Your search keyword '"Arianne Perez-Garcia"' showing total 3 results
Start Over Author "Arianne Perez-Garcia" Publisher american society of clinical oncology (asco)
3 results on '"Arianne Perez-Garcia"'

1. Association of melanoma expression of matrix metalloproteinase-23 with blunted tumor immunity and poor responses to immunotherapy

Author

Tianqi Li, Michelle W. Ma, Paul J. Christos, Duane Moogk, Ines Pires da Silva, Anna C. Pavlick, Erica B. Friedman, Michelle Krogsgaard, Nina Bhardwaj, Arianne Perez-Garcia, Iman Osman, Patrick Scanlon, Eleazar Vega-Saenz de Miera, Farbod Darvishian, and Chelsea Wei Ting Lee

Subjects
Cancer Research, business.industry, medicine.medical_treatment, T cell, Melanoma, Tumor immunity, Immunotherapy, Matrix (biology), Matrix metalloproteinase, medicine.disease, Potassium channel, medicine.anatomical_structure, Oncology, Cancer research, Medicine, business
Abstract

e20057 Background: Matrix metalloproteinase-23 (MMP-23) can inhibit T cell activation by selectively blocking the voltage-gated potassium channel Kv1.3, and may also alter T cell activity and pheno...

Published
2015
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2. Matrix metalloproteinase-23 as a new immunotherapeutic checkpoint target in melanoma

Author

Duane Moogk, Eleazar Vega-Saenz de Miera, Paul J. Christos, Anna C. Pavlick, Ines Pires da Silva, Arianne Perez-Garcia, Patrick Scanlon, Michelle Krogsgaard, Michelle W. Ma, Iman Osman, Nina Bhardwaj, Erica B. Friedman, and Farbod Darvishian

Subjects
Cancer Research, medicine.anatomical_structure, Oncology, T cell, Melanoma, Immunology, medicine, Cancer research, Biology, Matrix metalloproteinase, medicine.disease, Potassium channel
Abstract

3030 Background: Matrix metalloproteinase-23 (MMP-23) can inhibit T cell activation by selectively blocking the voltage-gated potassium channel Kv1.3, and may also alter T cell activity and phenoty...

Published
2014
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3. An analysis of altered melanoma matrix metalloproteinase-23 (MMP-23) expression and response to immune biologic therapy

Author

Michelle W. Ma, Russell S. Berman, Erica B. Friedman, Michelle Krogsgaard, Paul J. Christos, Iman Osman, Anna C. Pavlick, E. Vega-Saenz de Miera, Arianne Perez-Garcia, Richard L. Shapiro, and F. Darvishian

Subjects
Cancer Research, Immune system, Oncology, Downregulation and upregulation, business.industry, Melanoma, Immunology, Cancer research, Medicine, Matrix metalloproteinase, business, medicine.disease
Abstract

8541 Background: MMP-23, characterized by its unique ShK and immunoglobulin-like domains, has been shown to downregulate the immune response. The ShK domain selectively blocks the voltage-gated pot...

Published
2011
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