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1. Thymidylate synthetase as target enzyme for the inhibitory activity of 5-substituted 2'-deoxyuridines on mouse leukemia L1210 cell growth.

Author

De Clercq E, Balzarini J, Torrence PF, Mertes MP, Schmidt CL, Shugar D, Barr PJ, Jones AS, Verhelst G, and Walker RT

Subjects
Animals, Cell-Free System, Cells, Cultured, Deoxyuridine metabolism, Deoxyuridine pharmacology, Kinetics, Leukemia L1210 drug therapy, Mice, Antineoplastic Agents pharmacology, Deoxyuridine analogs & derivatives, Leukemia L1210 enzymology, Methyltransferases metabolism, Thymidylate Synthase metabolism
Published
1981

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