1. On the Emergence of <named-content content-type='genus-species'>Candida auris</named-content>: Climate Change, Azoles, Swamps, and Birds
- Author
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Arturo Casadevall, Dimitrios P. Kontoyiannis, Vincent Robert, Westerdijk Fungal Biodiversity Institute - Software and Databasing, and Westerdijk Fungal Biodiversity Institute
- Subjects
Azoles ,Antifungal Agents ,Letter ,Zoology ,Climate change ,Human pathogen ,Close relatives ,Microbial Sensitivity Tests ,Fungus ,Biology ,Communicable Diseases, Emerging ,Swamp ,Microbiology ,Birds ,03 medical and health sciences ,Drug Resistance, Multiple, Fungal ,Virology ,Animals ,Humans ,Clade ,Phylogeny ,030304 developmental biology ,Candida ,0303 health sciences ,geography ,geography.geographical_feature_category ,Phylogenetic tree ,030306 microbiology ,fungus ,Candidiasis ,Temperature ,biology.organism_classification ,QR1-502 ,Fungal disease ,climate change ,Candida auris ,13. Climate action - Abstract
The most enigmatic aspect of the rise of Candida auris as a human pathogen is that it emerged simultaneously on three continents, with each clade being genetically distinct. Although new pathogenic fungal species are described regularly, these are mostly species associated with single cases in individuals who are immunosuppressed.The most enigmatic aspect of the rise of Candida auris as a human pathogen is that it emerged simultaneously on three continents, with each clade being genetically distinct. Although new pathogenic fungal species are described regularly, these are mostly species associated with single cases in individuals who are immunosuppressed. In this study, we used phylogenetic analysis to compare the temperature susceptibility of C. auris with those of its close relatives and to use these results to argue that it may be the first example of a new fungal disease emerging from climate change, with the caveat that many other factors may have contributed.
- Published
- 2019
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