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Start Over Author "Stephen J Popper" Publisher american society for microbiology
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1. Low Plasma Human Immunodeficiency Virus Type 2 Viral Load Is Independent of Proviral Load: Low Virus Production In Vivo

Author

Phyllis J. Kanki, Abdoulaye Dieng Sarr, Aissatou Guèye-Ndiaye, Stephen J. Popper, Souleymane Mboup, and Myron Essex

Subjects
viruses, Immunology, Cell, Human immunodeficiency virus (HIV), Replication, HIV Infections, Biology, medicine.disease_cause, Microbiology, Virus, Cohort Studies, Proviruses, In vivo, Virology, medicine, Humans, Infectivity, virus diseases, RNA, Viral Load, Provirus, Sex Work, CD4 Lymphocyte Count, medicine.anatomical_structure, Insect Science, DNA, Viral, HIV-2, RNA, Viral, Female, Viral load
Abstract

Levels of virus in the plasma are closely related to the pathogenicity of human immunodeficiency virus type 1 (HIV-1). HIV-2 is much less pathogenic than HIV-1, and infection with HIV-2 leads to significantly lower plasma viral load. To identify the source of this difference, we measured both viral RNA and proviral DNA in matched samples from 34 HIV-2-infected individuals. Nearly half had undetectable viral RNA loads (

Published
2000
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