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Your search keyword '"Rivas, Marta"' showing total 17 results
Start Over Author "Rivas, Marta" Publisher american society for microbiology
17 results on '"Rivas, Marta"'

1. Development and Evaluation of a Novel VHH-Based Immunocapture Assay for High-Sensitivity Detection of Shiga Toxin Type 2 (Stx2) in Stool Samples

Author

Melli, Luciano J., primary, Zylberman, Vanesa, additional, Hiriart, Yanina, additional, Lauche, Constanza E., additional, Baschkier, Ariela, additional, Pardo, Romina, additional, Miliwebsky, Elizabeth, additional, Chinen, Isabel, additional, Rivas, Marta, additional, Goldbaum, Fernando A., additional, Ugalde, Juan E., additional, Comerci, Diego J., additional, and Ciocchini, Andrés E., additional

Published
2020
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3. Retinoid levels influence enterohemorrhagic Escherichia coli infection and shiga toxin susceptibility in mice

Author

Cabrera, Gabriel Gustavo, Fernández Brando, Romina Jimena, Abrey Recalde, Maria Jimena, Baschkier, Ariela, Vasconcelos Esteves Pinto, Alipio, Goldstein Raij, Jorge, Zotta, Elsa, Meiss, Roberto, Rivas, Marta, and Palermo, Marina Sandra

Subjects
ENTEROHEMORRHAGIC ESCHERICHIA COLI, Medicina Básica, MICE, CIENCIAS MÉDICAS Y DE LA SALUD, HEMOLYTIC UREMIC SYNDROME, RETINOIC ACID, Inmunología, purl.org/becyt/ford/3 [https], purl.org/becyt/ford/3.1 [https]
Abstract

Enterohemorrhagic Escherichia coli (EHEC) is a food-borne pathogen that produces Shiga toxin (Stx) and causes hemorrhagic colitis. Under some circumstances, Stx produced within the intestinal tract enters the bloodstream, leading to systemic complications that may cause the potentially fatal hemolytic-uremic syndrome. Although retinoids like vitamin A (VA) and retinoic acid (RA) are beneficial to gut integrity and the immune system, the effect of VA supplementation on gastrointestinal infections of different etiologies has been controversial. Thus, the aim of this work was to study the influence of different VA status on the outcome of an EHEC intestinal infection in mice. We report that VA deficiency worsened the intestinal damage during EHEC infection but simultaneously improved survival. Since death is associated mainly with Stx toxicity, Stx was intravenously inoculated to analyze whether retinoid levels affect Stx susceptibility. Interestingly, while VA-deficient (VA-D) mice were resistant to a lethal dose of Stx2, RA-supplemented mice were more susceptible to it. Given that peripheral blood polymorphonuclear cells (PMNs) are known to potentiate Stx2 toxicity, we studied the influence of retinoid levels on the absolute number and function of PMNs. We found that VA-D mice had decreased PMN numbers and a diminished capacity to produce reactive oxygen species, while RA supplementation had the opposite effect. These results are in line with the well-known function of retinoids in maintaining the homeostasis of the gut but support the idea that they have a proinflammatory effect by acting, in part, on the PMN population. Fil: Cabrera, Gabriel Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental; Argentina. Academia Nacional de Medicina de Buenos Aires; Argentina Fil: Fernández Brando, Romina Jimena. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental; Argentina. Academia Nacional de Medicina de Buenos Aires; Argentina Fil: Abrey Recalde, Maria Jimena. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental; Argentina. Academia Nacional de Medicina de Buenos Aires; Argentina Fil: Baschkier, Ariela. Direccion Nacional de Instituto de Investigacion. Adm.nacional de Laboratorio E Instituto de Salud "dr.c.g.malbran". Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriologia; Argentina Fil: Vasconcelos Esteves Pinto, Alipio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Neurofisiología; Argentina Fil: Goldstein Raij, Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Neurofisiología; Argentina Fil: Zotta, Elsa. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; Argentina Fil: Meiss, Roberto. Academia Nacional de Medicina de Buenos Aires; Argentina Fil: Rivas, Marta. Direccion Nacional de Instituto de Investigacion. Adm.nacional de Laboratorio E Instituto de Salud "dr.c.g.malbran". Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriologia; Argentina Fil: Palermo, Marina Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental; Argentina. Academia Nacional de Medicina de Buenos Aires; Argentina

Published
2014

8. Genetic Diversity and Virulence Potential of Shiga Toxin-Producing Escherichia coli O113:H21 Strains Isolated from Clinical, Environmental, and Food Sources

Author

Feng, Peter C. H., primary, Delannoy, Sabine, additional, Lacher, David W., additional, dos Santos, Luis Fernando, additional, Beutin, Lothar, additional, Fach, Patrick, additional, Rivas, Marta, additional, Hartland, Elizabeth L., additional, Paton, Adrienne W., additional, and Guth, Beatriz E. C., additional

Published
2014
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9. Protection of Mice against Shiga Toxin 2 (Stx2)-Associated Damage by Maternal Immunization with a Brucella Lumazine Synthase-Stx2 B Subunit Chimera

Author

Mejias, María Pilar, primary, Cabrera, Gabriel, additional, Fernández-Brando, Romina Jimena, additional, Baschkier, Ariela, additional, Ghersi, Giselle, additional, Abrey-Recalde, Maria Jimena, additional, Miliwebsky, Elizabeth, additional, Meiss, Roberto, additional, Goldbaum, Fernando, additional, Zylberman, Vanesa, additional, Rivas, Marta, additional, and Palermo, Marina Sandra, additional

Published
2014
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11. TccP2 of O157:H7 and Non-O157 Enterohemorrhagic Escherichia coli (EHEC): Challenging the Dogma of EHEC-Induced Actin Polymerization

Author

Ogura, Yoshitoshi, primary, Ooka, Tadasuke, additional, Whale, Andrew, additional, Garmendia, Junkal, additional, Beutin, Lothar, additional, Tennant, Sharon, additional, Krause, Gladys, additional, Morabito, Stefano, additional, Chinen, Isabel, additional, Tobe, Toru, additional, Abe, Hiroyuki, additional, Tozzoli, Rosangela, additional, Caprioli, Alfredo, additional, Rivas, Marta, additional, Robins-Browne, Roy, additional, Hayashi, Tetsuya, additional, and Frankel, Gad, additional

Published
2007
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16. Escherichia coli ehl1 Gene-Positive Serotype O18ac:H31 Associated with an Outbreak of Diarrhea in a Neonatal Nursery in Neuquén City, Argentina

Author

Chinen, Isabel, primary, Rivas, Marta, additional, Soriano, Viviana, additional, Miliwebsky, Elizabeth, additional, Galvez, Gabriel Fernández, additional, Chillemi, Germán, additional, Baschkier, Ariela, additional, Wang, Gehua, additional, Caldeira, Richard, additional, Woodward, David L., additional, and Rodgers, Frank G., additional

Published
2002
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