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Your search keyword '"Kerstin Svensson"' showing total 2 results
Start Over Author "Kerstin Svensson" Publisher american society for microbiology
2 results on '"Kerstin Svensson"'

1. Evolution of Subspecies of Francisella tularensis

Author

Kerstin Svensson, Pär Larsson, Mats Forsman, Anders Johansson, Daniel Johansson, and Mona Byström

Subjects
Genetics, Virulence, biology, Molecular Sequence Data, Subspecies, biology.organism_classification, Microbiology, Evolution, Molecular, Bacteriology, Francisella, Francisella tularensis, Molecular Biology, Gene, Population Genetics and Evolution, Gene Deletion, Genome, Bacterial, Phylogeny, Oligonucleotide Array Sequence Analysis
Abstract

Analysis of unidirectional genomic deletion events and single nucleotide variations suggested that the four subspecies of Francisella tularensis have evolved by vertical descent. The analysis indicated an evolutionary scenario where the highly virulent F. tularensis subsp. tularensis (type A) appeared before the less virulent F. tularensis subsp. holarctica (type B). Compared to their virulent progenitors, attenuated strains of F. tularensis exhibited specific unidirectional gene losses.

Published
2005
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2. Genome Sequence of Francisella tularensis subspecies holarctica Strain FSC200, Isolated from a Child with Tularemia

Author

Laurence Rohmer, Yang Zhou, Eric Haugen, Ruth Levy, Will Gillett, Mitchell J. Brittnacher, Hillary S. Hayden, Elizabeth H. Sims-Day, Kerstin Svensson, Jean Chang, Michael A. Jacobs, Donald Guenthener, Allison Kang, Pär Larsson, Mats Forsman, Malin Granberg, Rajinder Kaul, Anders Johansson, Regina Lim, Andreas Sjödin, and Mona Byström

Subjects
DNA, Bacterial, Molecular Sequence Data, Biology, Microbiology, Genome, complex mixtures, Tularemia, medicine, Humans, Base sequence, Francisella tularensis, Molecular Biology, Whole genome sequencing, Sweden, Base Sequence, Strain (biology), Francisella tularensis subspecies holarctica, Sequence Analysis, DNA, respiratory system, medicine.disease, biology.organism_classification, bacterial infections and mycoses, Virology, Genome Announcements, Bacterial Typing Techniques, Child, Preschool, Francisella, bacteria, Female, Genome, Bacterial
Abstract

Here we report the complete, accurate 1.89-Mb genome sequence of Francisella tularensis subsp. holarctica strain FSC200, isolated in 1998 in the Swedish municipality Ljusdal, which is in an area where tularemia is highly endemic. This genome is important because strain FSC200 has been extensively used for functional and genetic studies of Francisella and is well-characterized.

Published
2012

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