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Your search keyword '"Jan L. Nouwen"' showing total 2 results
Start Over Author "Jan L. Nouwen" Publisher american society for microbiology
2 results on '"Jan L. Nouwen"'

1. Clonal Distribution and Differential Occurrence of the Enterotoxin Gene Cluster, egc , in Carriage- versus Bacteremia-Associated Isolates of Staphylococcus aureus

Author

Heiman F. L. Wertheim, Jerome Etienne, Susan V. Snijders, Alex van Belkum, Willem B. van Leeuwen, Jan L. Nouwen, Damian C. Melles, Henri A. Verbrugh, and Medical Microbiology & Infectious Diseases

Subjects
DNA, Bacterial, Microbiology (medical), Staphylococcus aureus, Micrococcaceae, Epidemiology, Bacteremia, Locus (genetics), Enterotoxin, Staphylococcal infections, medicine.disease_cause, Microbiology, Enterotoxins, Gene cluster, medicine, Humans, Superantigens, biology, Staphylococcal Infections, biology.organism_classification, medicine.disease, Virology, Bacterial Typing Techniques, Multigene Family, Carrier State, Multilocus sequence typing
Abstract

The Staphylococcus aureus enterotoxin gene cluster, egc , was detected in isolates from healthy individuals and in those from patients with bacteremia. The egc genes cooccur and are slightly enriched in strains from healthy carriers (present in 63.7% of carriage-associated isolates versus 52.9% of invasive isolates; P = 0.03). Multilocus sequence typing revealed that successful staphylococcal clones usually harbor the egc locus.

Published
2006
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2. Staphylococcus aureus Carriage Patterns and the Risk of Infections Associated with Continuous Peritoneal Dialysis

Author

Peter Schneebergen, Susan V. Snijders, Jan L. Nouwen, Marjan Koolen, Henri A. Verbrugh, Alex van Belkum, Jeroen Schouten, Jolanda Maaskant, Medical Microbiology & Infectious Diseases, and Medical Oncology

Subjects
Microbiology (medical), Adult, Male, medicine.medical_specialty, Staphylococcus aureus, Adolescent, Epidemiology, medicine.medical_treatment, education, Nose, medicine.disease_cause, Staphylococcal infections, Peritoneal dialysis, Peritoneal Dialysis, Continuous Ambulatory, Risk Factors, Internal medicine, medicine, Humans, Aged, business.industry, Catheter exit site, Middle Aged, Staphylococcal Infections, medicine.disease, Surgery, Pathogenesis and modulation of inflammation [N4i 1], medicine.anatomical_structure, Carriage, Carrier State, Vancomycin, Female, Microbial pathogenesis and host defense [UMCN 4.1], business, medicine.drug
Abstract

The epidemiology and risks of Staphylococcus aureus carriage in continuous peritoneal dialysis (CPD) patients was studied in a single tertiary-care institution. On outpatient visits samples for culture were routinely taken prospectively from the CPD catheter exit site and the vestibulum nasi. Seventy-five patients with at least one culture positive for S. aureus in this period were included: 43 had genotypically identical S. aureus strains in over 80% of the cultures and were classified as persistent carriers; 32 were intermittent carriers. Persistent carriage was associated with a threefold higher risk for CPD-related infections and sixfold higher rates of vancomycin consumption compared to those for the intermittent carriers. No methicillin or vancomycin resistance was detected.

Published
2006

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