1. Invasive pulmonary aspergillosis due to Emericella nidulans var. echinulata, successfully cured by voriconazole and micafungin.
- Author
-
Yu J, Mu X, and Li R
- Subjects
- Aged, DNA, Fungal chemistry, DNA, Fungal genetics, Emericella classification, Emericella genetics, Exudates and Transudates microbiology, Galactose analogs & derivatives, Glucocorticoids administration & dosage, Glucocorticoids adverse effects, Humans, Immunocompromised Host, Invasive Pulmonary Aspergillosis microbiology, Male, Mannans analysis, Micafungin, Microscopy, Molecular Sequence Data, Sequence Analysis, DNA, Treatment Outcome, Voriconazole, Antifungal Agents administration & dosage, Echinocandins administration & dosage, Emericella isolation & purification, Invasive Pulmonary Aspergillosis diagnosis, Invasive Pulmonary Aspergillosis drug therapy, Lipopeptides administration & dosage, Pyrimidines administration & dosage, Triazoles administration & dosage
- Abstract
A 78-year-old male who was undergoing prolonged glucocorticoid treatment experienced cough and expectoration for 2 weeks. Galactomannan antigen analysis and a chest computed tomography (CT) scan suggested a diagnosis of invasive pulmonary aspergillosis. DNA sequencing indicated that Emericella nidulans var. echinulata was the causative agent. A combination of voriconazole and micafungin successfully treated the illness.
- Published
- 2013
- Full Text
- View/download PDF