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Start Over Author "Christophe Loup" Publisher american society for microbiology
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1. Trioxaquines and Heme-Artemisinin Adducts Inhibit the In Vitro Formation of Hemozoin Better than Chloroquine

Author

Françoise Benoit-Vical, Bernard Meunier, Joël Lelièvre, and Christophe Loup

Subjects
Hemeproteins, Plasmodium, Artemisinins, Alkylation, Spectrophotometry, Infrared, Heme, Dioxanes, Antimalarials, chemistry.chemical_compound, Chloroquine, parasitic diseases, polycyclic compounds, medicine, Animals, Pharmacology (medical), Antimalarial Agent, Artemisinin, Mechanisms of Action: Physiological Effects, Pharmacology, Chemistry, Hemozoin, In vitro, Infectious Diseases, Biochemistry, Sesquiterpenes, medicine.drug
Abstract

Trioxaquines, potential antimalarial agents, and heme-artemisinin adducts, resulting from the alkylation of heme by artemisinin, were evaluated as inhibitors of β-hematin formation in 10 M acetate medium at pH 5.

Published
2007
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