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Intimate partner violence (IPV) is an enormous public health problem that results in injury, health problems, and substantial cost to society. Despite having a grasp of the scope of IPV, public health officials and workers know little about how to prevent it. The few empirically established primary prevention programs consist of school-based curricula targeting high school students. Additional venues for IPV prevention are needed, especially for women at elevated risk. This article describes a preventive intervention for IPV consisting of three components: (a) a structured assessment for IPV; (b) a brochure-driven intervention for women experiencing IPV, including safety planning, referrals, and advocacy; and (c) a skills-based curriculum delivered to all participants that focuses on improving relationship decisions and outcomes. While this intervention could potentially be delivered in a multitude of clinical settings, this article focuses on its delivery within a home visitation program for young, disadvantaged new mothers, a population known to be at increased risk for IPV. If found to be effective, this intervention could be incorporated into many service delivery systems, with broad-based clinical implications for IPV prevention.