1. Dissociation, Hemispheric Asymmetry, and Dysfunction of Hemispheric Interaction: A Transcranial Magnetic Stimulation Approach
- Author
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Carsten Spitzer, Timolaos Rizos, Harald J. Freyberger, Hans-Joergen Grabe, Carsten Willert, and Bertram Möller
- Subjects
Adult ,Male ,Dissociation (neuropsychology) ,Adolescent ,medicine.drug_class ,medicine.medical_treatment ,Pyramidal Tracts ,Dissociative Experiences Scale ,Dissociative Disorders ,Dissociative ,Corpus callosum ,Functional Laterality ,Statistics, Nonparametric ,Corpus Callosum ,Electromagnetic Fields ,Hemispheric asymmetry ,medicine ,Humans ,Chi-Square Distribution ,Motor Cortex ,Evoked Potentials, Motor ,Transcranial magnetic stimulation ,Psychiatry and Mental health ,Cerebral hemisphere ,Female ,Neurology (clinical) ,Psychology ,Neuroscience ,Conduction time - Abstract
The authors investigated the hypothesis that dissociation may represent a functional dysconnectivity syndrome using a transcranial magnetic stimulation (TMS) approach. Transcranial magnetic stimulation investigations that included motor thresholds and the transcallosal conduction time (TCT) reflecting the interhemispheric transfer were performed in 74 right-handed students. All subjects completed the Dissociative Experience Scale. The high dissociators had a significantly lower left hemispheric excitability than right hemispheric excitability. They also had a significantly shorter TCT from the left to the right hemisphere than did the low dissociators. These results suggest that the neural basis of dissociation may involve a cortical asymmetry with a left hemispheric superiority or, alternatively, a lack of right hemispheric integration.
- Published
- 2004