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Key Points Question Is a wrist-worn frailty meter (FM) that quantifies physical frailty using a 20-second repetitive elbow flexion-extension test a feasible tool for evaluating the risk of 30-day major adverse events (MAEs) after lower-limb revascularization? Findings In this 2-center cohort-study of 152 patients, all participants were able to perform the FM test within 1 week before revascularization, whereas most were unable to perform a gait test because of the presence of foot ulcers. The FM distinguished between those with and without 30-day MAEs. Meaning The results of this study suggest that the FM is feasible and may support surgeons in evaluating the risks and benefits of revascularization in older adults., This cohort study tests a frailty meter that does not rely on gait to determine the risk of 30-day major adverse events among patients with chronic limb-threatening ischemia who have undergone lower extremity revascularization., Importance Physical frailty is a key risk factor associated with higher rates of major adverse events (MAEs) after surgery. Assessing physical frailty is often challenging among patients with chronic limb-threatening ischemia (CLTI) who are often unable to perform gait-based assessments because of the presence of plantar wounds. Objective To test a frailty meter (FM) that does not rely on gait to determine the risk of occurrence of MAEs after revascularization for patients with CLTI. Design, Setting, and Participants This cohort study included 184 consecutively recruited patients with CLTI at 2 tertiary care centers. After 32 individuals were excluded, 152 participants were included in the study. Data collection was conducted between May 2018 and June 2019. Exposures Physical frailty measurement within 1 week before limb revascularization and incidence of MAEs for as long as 1 month after surgery. Main Outcomes and Measures The FM works by quantifying weakness, slowness, rigidity, and exhaustion during a 20-second repetitive elbow flexion-extension exercise using a wrist-worn sensor. The FM generates a frailty index (FI) ranging from 0 to 1; higher values indicate progressively greater severity of physical frailty. Results Of 152 eligible participants (mean [SD] age, 67.0 [11.8] years; 59 [38.8%] women), 119 (78.2%) were unable to perform the gait test, while all could perform the FM test. Overall, 53 (34.9%), 58 (38.1%), and 41 (27.0%) were classified as robust (FI