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Your search keyword '"Lee, Sei J"' showing total 27 results
Start Over Author "Lee, Sei J" Publisher american medical association (ama)
27 results on '"Lee, Sei J"'

6. Comparison of 6 Mortality Risk Scores for Prediction of 1-Year Mortality Risk in Older Adults With Multimorbidity

Author

Schneider, Claudio, primary, Aubert, Carole E., additional, Del Giovane, Cinzia, additional, Donzé, Jacques D., additional, Gastens, Viktoria, additional, Bauer, Douglas C., additional, Blum, Manuel R., additional, Dalleur, Olivia, additional, Henrard, Séverine, additional, Knol, Wilma, additional, O’Mahony, Denis, additional, Curtin, Denis, additional, Lee, Sei J., additional, Aujesky, Drahomir, additional, Rodondi, Nicolas, additional, and Feller, Martin, additional

Published
2022
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7. Comparison of 6 Mortality Risk Scores for Prediction of 1-Year Mortality Risk in Older Adults With Multimorbidity

Author

UCL - SSS/LDRI - Louvain Drug Research Institute, UCL - SSS/IRSS - Institut de recherche santé et société, UCL - (SLuc) Département de pharmacie, Schneider, Claudio, Aubert, Carole E., Del Giovane, Cinzia, Donzé, Jacques D., Gastens, Viktoria, Bauer, Douglas C., Blum, Manuel R., Dalleur, Olivia, Henrard, Séverine, Knol, Wilma, O’Mahony, Denis, Curtin, Denis, Lee, Sei J., Aujesky, Drahomir, Rodondi, Nicolas, Feller, Martin, UCL - SSS/LDRI - Louvain Drug Research Institute, UCL - SSS/IRSS - Institut de recherche santé et société, UCL - (SLuc) Département de pharmacie, Schneider, Claudio, Aubert, Carole E., Del Giovane, Cinzia, Donzé, Jacques D., Gastens, Viktoria, Bauer, Douglas C., Blum, Manuel R., Dalleur, Olivia, Henrard, Séverine, Knol, Wilma, O’Mahony, Denis, Curtin, Denis, Lee, Sei J., Aujesky, Drahomir, Rodondi, Nicolas, and Feller, Martin

Abstract

Importance: The most appropriate therapy for older adults with multimorbidity may depend on life expectancy (ie, mortality risk), and several scores have been developed to predict 1-year mortality risk. However, often, these mortality risk scores have not been externally validated in large sample sizes, and a head-to-head comparison in a prospective contemporary cohort is lacking. Objective: To prospectively compare the performance of 6 scores in predicting the 1-year mortality risk in hospitalized older adults with multimorbidity. Design, setting, and participants: This prognostic study analyzed data of participants in the OPERAM (Optimising Therapy to Prevent Avoidable Hospital Admissions in Multimorbid Older People) trial, which was conducted between December 1, 2016, and October 31, 2018, in surgical and nonsurgical departments of 4 university-based hospitals in Louvain, Belgium; Utrecht, the Netherlands; Cork, Republic of Ireland; and Bern, Switzerland. Eligible participants in the OPERAM trial had multimorbidity (≥3 coexisting chronic diseases), were aged 70 years or older, had polypharmacy (≥5 long-term medications), and were admitted to a participating ward. Data were analyzed from April 1 to September 30, 2020. Main outcomes and measures: The outcome of interest was any-cause death occurring in the first year of inclusion in the OPERAM trial. Overall performance, discrimination, and calibration of the following 6 scores were assessed: Burden of Illness Score for Elderly Persons, CARING (Cancer, Admissions ≥2, Residence in a nursing home, Intensive care unit admit with multiorgan failure, ≥2 Noncancer hospice guidelines) Criteria, Charlson Comorbidity Index, Gagné Index, Levine Index, and Walter Index. These scores were assessed using the following measures: Brier score (0 indicates perfect overall performance and 0.25 indicates a noninformative model); C-statistic and 95% CI; Hosmer-Lemeshow goodness-of-fit test and calibration plots; and sensitivity, speci

Published
2022

10. Evaluation of Time to Benefit of Statins for the Primary Prevention of Cardiovascular Events in Adults Aged 50 to 75 Years

Author

Yourman, Lindsey C., primary, Cenzer, Irena S., additional, Boscardin, W. John, additional, Nguyen, Brian T., additional, Smith, Alexander K., additional, Schonberg, Mara A., additional, Schoenborn, Nancy L., additional, Widera, Eric W., additional, Orkaby, Ariela, additional, Rodriguez, Annette, additional, and Lee, Sei J., additional

Published
2021
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15. Association of β-Blockers With Functional Outcomes, Death, and Rehospitalization in Older Nursing Home Residents After Acute Myocardial Infarction

Author

Steinman, Michael A., primary, Zullo, Andrew R., additional, Lee, Yoojin, additional, Daiello, Lori A., additional, Boscardin, W. John, additional, Dore, David D., additional, Gan, Siqi, additional, Fung, Kathy, additional, Lee, Sei J., additional, Komaiko, Kiya D. R., additional, and Mor, Vincent, additional

Published
2017
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