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Attenuated measles-virus vaccine and gamma globulin were administered to a group of children, while another group of randomly selected controls received only gamma globulin. Six of 8 nonimmune vaccinees, and 3 of 9 controls developed febrile episodes of 38.1° C. (100.6° F.) or greater from 4 to 14 days after inoculation. The febrile episodes experienced by the vaccinees were probably due both to vaccine reactions and to intercurrent infections, since the controls tended to develop fewer and milder febrile episodes. None of the vaccinees developed either Koplik spots or a rash. Thirteen of 14 nonimmune vaccinees developed measles hemagglutination inhibition antibody after vaccination. During an outbreak, all of 12 controls and only one of 10 vaccinees developed measles, indicating that the vaccination had rendered significant protection.

As part of a study on eosinophilic meningitis in the Pacific area, postmortem material was examined from 2 mental patients who died in Hawaii with an eosinophilic meningoencephalitis. A number of young adult nematodes, identified asAngiostrongylus cantonensis, a rat lungworm, were found in the brain and meninges of 1 patient. Foreign material in the brain of the second patient and a cellular reaction similar to that observed in the first case suggested that this person also may have been infected with the same parasite. The presence of other abnormalities precluded an attempt to determine how many of either patient's symptoms might have been caused by this parasite. It was also not determined how either patient may have become infected.