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Start Over Author "Greenberg, Andrew S." Publisher american medical association
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1. Recombinant Leptin for Weight Loss in Obese and Lean Adults: A Randomized, Controlled, Dose-Escalation Trial

Author

Heymsfield, Steven B., Greenberg, Andrew S., Fujioka, Ken, Dixon, Russell M., Kushner, Robert, Hunt, Thomas, Lubina, John A., Patane, Janet, Self, Barbara, Hunt, Pam, and McCamish, Mark

Subjects
Leptin -- Health aspects, Obesity -- Care and treatment
Abstract

Recombinant human leptin appears to cause weight loss in some obese people. Leptin is a naturally occurring hormone in the human body that seems to regulate fat metabolism. Researchers randomly assigned 54 normal-weight men and women and 73 obese men and women to give themselves daily subcutaneous injections of recombinant leptin or a placebo. Leptin caused weight loss in both groups and the more leptin was used, the more weight was lost. No side effects were noted except for mild reactions at the injection site.

Published
1999

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