For hundreds of years prior to the space age, Venus was considered among the most likely homes for extraterrestrial life. Since planetary exploration began, Venus has not been considered a promising target for Astrobiological exploration. However, Venus should be central to such an exploration program for several reasons. At present Venus is the only other Earth-sized terrestrial planet that we know of, and certainly the only one we will have the opportunity to explore in the foreseeable future. Understanding the divergence of Earth and Venus is central to understanding the limits of habitability in the inner regions of habitable zones around solar-type stars. Thus Venus presents us with a unique opportunity for putting the bulk properties, evolution and ongoing geochemical processes of Earth in a wider context. Many geological and meteorological processes otherwise active only on Earth at present are currently active on Venus. Active volcanism most likely affects the climate and chemical equilibrium state of the atmosphere and surface, and maintains the global cloud cover. Further, if we think beyond the specifics of a particular chemical system required to build complexity and heredity, we can ask what general properties a planet must possess in order to be considered a possible candidate for life. The answers might include an atmosphere with signs of flagrant chemical disequilibrium and active, internally driven cycling of volatile elements between the surface, atmosphere and interior. At present, the two planets we know of which possess these characteristics are Earth and Venus. Venus almost surely once had warm, habitable oceans. The evaporation of these oceans, and subsequent escape of hydrogen, most likely resulted in an oxygenated atmosphere. The duration of this phase is poorly understood, but during this time the terrestrial planets were not isolated. Rather, due to frequent impact transport, they represented a continuous environment for early microbial life. Life, once established in the early oceans of Venus, may have migrated to the clouds which, on present day Venus, may represent a habitable niche. Though highly acidic, this aqueous environment enjoys moderate temperatures, surroundings far from chemical equilibrium, and potentially useful radiation fluxes. Observations of unusual chemistry in the clouds, and particle-populations that are not well characterized, suggest that this environment must be explored much more fully before biology can be ruled out. A sulfur-based metabolism for cloud-based life on Venus has recently been proposed (Schulze-Makuch et al., 2004). While speculative, these arguments, along with the discovery of terrestrial extremophile organisms that point toward the plausibility of survival in the Venusian clouds, establish the credibility of astrobiological exploration of Venus. Arguments for the possible existence of life on Mars or Europa are, by convention and repetition, seen as more mainstream than arguments for life elsewhere, but their logical status is similar to plausibility arguments for life on Venus. With the launch of COROT in 2006 and Kepler in 2008 the demographics of Earth-sized planets in our galaxy should finally become known. Future plans for a Terrestrial Planet Finder or Darwin-type space-based spectrograph should provide the capability of studying the atmospheric composition and other properties of terrestrial planets. One of the prime rationales for building such instruments is the possibility of identifying habitable planets or providing more generalized observational constraints on the habitable zones of stellar systems. Given the prevalence of CO 2 dominated atmospheres in our own solar system, it is quite likely that a large fraction of these will be Venus-like in composition and evolutionary history. We will be observing these planets at random times in their evolution. In analogy with our own solar system, it is just as likely that we will find representatives of early Venus and early Earth type planets from the first 2 billion years of their evolution as it is that we will find "mature Venus" and "mature Earth" type planets that are roughly 4.5 billion years old. Therefore, in order to be poised to use the results of these future observations of extrasolar planets to make valid, generalized inferences about the size, shape and evolution of stellar habitable zones it is vital that we obtain a much deeper understanding of the evolutionary histories and divergence of Earth and Venus. The Mars Exploration Rover findings of evidence for aqueous conditions on early Mars have intensified interest in the possible origin and evolution of life on early Mars. Yet the evidence suggests that these deposits were formed in a highly acidic and sulfur-rich environment. During this phase, Mars may well have had sulfuric acid clouds sustained by vigorous, sulfur-rich volcanism. This suggests that a greater understanding of the chemistry of the Venusian atmosphere and clouds, and surface/atmosphere interactions, may help to characterize the environment of Mars when life may have formed there. In turn, if signs of early life are found on Mars during the upcoming decades of intensive astrobiological exploration planned for that planet, it will strengthen arguments for the plausibility of life in an early and gradually acidifying Venusian environment. Of our two neighboring planets, Venus and Mars, it is not yet known which held on to its surface oceans, and early habitable conditions, for longer.