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Start Over Author "S R, Waltman" Publisher american diabetes association
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3. Effect of Blood Glucose Control on Retinal Vascular Permeability in Insulin-dependent Diabetes Mellitus

Author

L Schachter, R Bernstein, S R Waltman, R Temes, T Krupin, S J Bleicher, T Y Lee, B Becker, and Julio V. Santiago

Subjects
Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Population, Blood sugar, Vascular permeability, Retina, Capillary Permeability, chemistry.chemical_compound, Internal medicine, Diabetes mellitus, Diabetes Mellitus, Internal Medicine, medicine, Humans, Insulin, education, Advanced and Specialized Nursing, education.field_of_study, business.industry, Fluorophotometry, Hemoglobin A, Retinal, medicine.disease, Endocrinology, chemistry, Regular insulin, Female, business
Abstract

Thirteen patients were instructed in a technique of self-management of insulin-dependent diabetes mellitus, using multiple home-monitored blood glucose determinations and multiple injections of regular insulin in conjunction with once-daily Ultra Lente insulin. Hemoglobin A1c and quantitative fluorescein fluorophotometry were used to assess blood glucose control and retinal permeability, respectively. In those patients achieving normal blood glucose control, retinal vascular leakage was statistically identical to that of a nondiabetic control population. In those patients less well controlled, retinal permeability did not differ statistically from values observed in a population of insulin-dependent diabetic patients under “standard” control. It is concluded that with “tight” control of blood sugar and normalized A1c hemoglobin, retinal permeability similarly is normalized.

Published
1980
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