Search

Your search keyword '"Ippolito, Elio"' showing total 5 results
Start Over Author "Ippolito, Elio" Publisher american diabetes association
5 results on '"Ippolito, Elio"'

1. Indirect and Direct Effects of SARS-CoV-2 on Human Pancreatic Islets

Author

Nasr, Moufida Ben, primary, D’Addio, Francesca, primary, Montefusco, Laura, primary, Usuelli, Vera, primary, Loretelli, Cristian, primary, Rossi, Antonio, primary, Pastore, Ida, primary, Abdelsalam, Ahmed, primary, Maestroni, Anna, primary, Dell’Acqua, Marco, primary, Ippolito, Elio, primary, Assi, Emma, primary, Seelam, Andy Joe, primary, Fiorina, Roberta Maria, primary, Chebat, Enrica, primary, Morpurgo, Paola, primary, Lunati, Maria Elena, primary, Bolla, Andrea Mario, primary, Abdi, Reza, primary, Bonventre, Joseph V., primary, Rusconi, Stefano, primary, Riva, Agostino, primary, Corradi, Domenico, primary, Santus, Pierachille, primary, Clark, Pamela, primary, Nebuloni, Manuela, primary, Baldi, Gabriella, primary, Finzi, Giovanna, primary, Folli, Franco, primary, Zuccotti, Gian Vincenzo, primary, Galli, Massimo, primary, Herold, Kevan C., primary, and Fiorina, Paolo, primary

Published
2022
Full Text
View/download PDF

2. Indirect and Direct Effects of SARS-CoV-2 on Human Pancreatic Islets

Author

Ben Nasr, Moufida, primary, D’Addio, Francesca, additional, Montefusco, Laura, additional, Usuelli, Vera, additional, Loretelli, Cristian, additional, Rossi, Antonio, additional, Pastore, Ida, additional, Abdelsalam, Ahmed, additional, Maestroni, Anna, additional, Dell’Acqua, Marco, additional, Ippolito, Elio, additional, Assi, Emma, additional, Seelam, Andy Joe, additional, Fiorina, Roberta Maria, additional, Chebat, Enrica, additional, Morpurgo, Paola, additional, Lunati, Maria Elena, additional, Bolla, Andrea Mario, additional, Abdi, Reza, additional, Bonventre, Joseph V., additional, Rusconi, Stefano, additional, Riva, Agostino, additional, Corradi, Domenico, additional, Santus, Pierachille, additional, Clark, Pamela, additional, Nebuloni, Manuela, additional, Baldi, Gabriella, additional, Finzi, Giovanna, additional, Folli, Franco, additional, Zuccotti, Gian Vincenzo, additional, Galli, Massimo, additional, Herold, Kevan C., additional, and Fiorina, Paolo, additional

Published
2022
Full Text
View/download PDF

3. Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes

Author

Vecchione, Andrea, primary, Jofra, Tatiana, primary, Gerosa, Jolanda, primary, Shankwitz, Kimberly, primary, Fonte, Roberta Di, primary, Galvani, Giuseppe, primary, Ippolito, Elio, primary, Cicalese, Maria Pia, primary, Schultz, Andrew R., primary, Seay, Howie R., primary, Favellato, Mariagrazia, primary, Milardi, Giulia, primary, Stabilini, Angela, primary, Ragogna, Francesca, primary, Grogan, Pauline, primary, Bianconi, Eleonora, primary, Laurenzi, Andrea, primary, Caretto, Amelia, primary, Nano, Rita, primary, Melzi, Raffaela, primary, Danzl, Nichole, primary, Bosi, Emanuele, primary, Piemonti, Lorenzo, primary, Aiuti, Alessandro, primary, Brusko, Todd, primary, Petrovas, Constantinos, primary, Battaglia, Manuela, primary, and Fousteri, Georgia, primary

Published
2021
Full Text
View/download PDF

4. Sitagliptin Treatment at the Time of Hospitalization Was Associated With Reduced Mortality in Patients With Type 2 Diabetes and COVID-19: A Multicenter, Case-Control, Retrospective, Observational Study

Author

Solerte, Sebastiano Bruno, primary, D’Addio, Francesca, additional, Trevisan, Roberto, additional, Lovati, Elisabetta, additional, Rossi, Antonio, additional, Pastore, Ida, additional, Dell’Acqua, Marco, additional, Ippolito, Elio, additional, Scaranna, Cristiana, additional, Bellante, Rosalia, additional, Galliani, Silvia, additional, Dodesini, Alessandro Roberto, additional, Lepore, Giuseppe, additional, Geni, Francesca, additional, Fiorina, Roberta Maria, additional, Catena, Emanuele, additional, Corsico, Angelo, additional, Colombo, Riccardo, additional, Mirani, Marco, additional, De Riva, Carlo, additional, Oleandri, Salvatore Endrio, additional, Abdi, Reza, additional, Bonventre, Joseph V., additional, Rusconi, Stefano, additional, Folli, Franco, additional, Di Sabatino, Antonio, additional, Zuccotti, Gianvincenzo, additional, Galli, Massimo, additional, and Fiorina, Paolo, additional

Published
2020
Full Text
View/download PDF

5. Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes.

Author

Vecchione, Andrea, Jofra, Tatiana, Gerosa, Jolanda, Shankwitz, Kimberly, Di Fonte, Roberta, Galvani, Giuseppe, Ippolito, Elio, Cicalese, Maria Pia, Schultz, Andrew R., Seay, Howie R., Favellato, Mariagrazia, Milardi, Giulia, Stabilini, Angela, Ragogna, Francesca, Grogan, Pauline, Bianconi, Eleonora, Laurenzi, Andrea, Caretto, Amelia, Nano, Rita, and Melzi, Raffaela

Subjects
REGULATORY T cells, TYPE 1 diabetes, LYMPH nodes, SPLEEN, LABORATORY mice, AUTOIMMUNE diseases, PANCREAS, RESEARCH, CELL culture, ANIMAL experimentation, RESEARCH methodology, CASE-control method, EVALUATION research, COMPARATIVE studies, RESEARCH funding, LYMPHOCYTE count, MICE
Abstract

In the attempt to understand the origin of autoantibody (AAb) production in patients with and at risk for type 1 diabetes (T1D), multiple studies have analyzed and reported alterations in T follicular helper (Tfh) cells in presymptomatic AAb+ subjects and patients with T1D. Yet, whether the regulatory counterpart of Tfh cells, represented by T follicular regulatory (Tfr) cells, is similarly altered is still unclear. To address this question, we performed analyses in peripheral blood, spleen, and pancreatic lymph nodes (PLN) of organ donor subjects with T1D. Blood analyses were also performed in living AAb- and AAb+ subjects. While negligible differences in the frequency and phenotype of blood Tfr cells were observed among T1D, AAb-, and AAb+ adult subjects, the frequency of Tfr cells was significantly reduced in spleen and PLN of T1D as compared with nondiabetic control subjects. Furthermore, adoptive transfer of Tfr cells delayed disease development in a mouse model of T1D, a finding that could indicate that Tfr cells play an important role in peripheral tolerance and regulation of autoreactive Tfh cells. Together, our findings provide evidence of Tfr cell alterations within disease-relevant tissues in patients with T1D, suggesting a role for Tfr cells in defective humoral tolerance and disease pathogenesis. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results