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Discusses the underrepresentation of women in new drug trials. Medical risks faced by young women; Guidelines of the U.S. Food and Drug Administration on drugs given to pregnant women; Extent of underrepresentation.

Describes a patient with orthostatic hypotension and congestive heart failure with primary amyloidosis. Clinical manifestation of systemic amyloidosis; Description of the patient; Laboratory findings on the patient; Treatment administered to the patient.

Focuses on a study which investigated the peripheral physiology in patients with systemic amyloidosis. Assessment of forearm blood flow response; Case histories on the medical condition; Results of forearm vascular dynamics.

Editorial. Focuses on the effectiveness of cardiovascular drugs. Information on calcium blocker therapy; Schematic representation of the mechanisms involved in vascular smooth muscle contraction and relaxation; Discussion on vascular smooth muscle contraction.