22 results on '"Salituro Francesco G"'
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2. Impact of Allosteric Modulation in Drug Discovery: Innovation in Emerging Chemical Modalities
3. Neuroactive Steroid N-Methyl-d-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological Activity
4. Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers
5. Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases
6. Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)AReceptor: Structure–Activity Relationships of Heterocyclic Substitution at C-21
7. Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2
8. Multisubstrate Inhibition of 4-Hydroxybenzoate 3-Monooxygenase
9. Enzyme-Activated Antagonists of the Strychnine-Insensitive Glycine/NMDA Receptor
10. 3-(2-Carboxyindol-3-yl)propionic acid derivatives: antagonists of the strychnine-insensitive glycine receptor associated with the N-methyl-D-aspartate receptor complex
11. Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo
12. The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor
13. Janus Kinase 2 Inhibitors. Synthesis and Characterization of a Novel Polycyclic Azaindole
14. Multisubstrate Inhibition of 4-Hydroxybenzoate 3-Monooxygenase
15. Enzyme-Activated Antagonists of the Strychnine-Insensitive Glycine/NMDA Receptor
16. 3-(2-Carboxyindol-3-yl)propionic acid-based antagonists of the NMDA (N-methyl-D-aspartic acid) receptor associated glycine binding site
17. 3-(2-Carboxyindol-3-yl)propionic acid derivatives: antagonists of the strychnine-insensitive glycine receptor associated with the N-methyl-D-aspartate receptor complex
18. Inhibition of aspartic proteinases by peptides containing lysine and ornithine side-chain analogs of statine
19. Facile synthesis of L-kynurenine
20. Synthetic and enzyme inhibition studies of pepstatin analogs containing hydroxyethylene and ketomethylene dipeptide isosteres
21. Synthesis of analogs of pepstatin. Effect of structure in subsites P1', P2', and P2 on inhibition of porcine pepsin
22. Inhibition of aspartic proteases by pepstatin and 3-methylstatine derivatives of pepstatin. Evidence for collected-substrate enzyme inhibition
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