Author: "M von Strandtmann" / Publisher: american chemical society (acs) - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "M von Strandtmann" Publisher american chemical society (acs)

Author: M von Strandtmann and David T. Connor
Subjects: Antifungal Agents, Ketone, Stereochemistry, Alcohol, medicine.disease_cause, Aldehyde, Structure-Activity Relationship, chemistry.chemical_compound, fluids and secretions, Oximes, Drug Discovery, medicine, Structure–activity relationship, Myxococcales, Candida albicans, Pyrans, chemistry.chemical_classification, Aldehydes, Bacteria, biology, Fungi, Chemical modification, Ketones, bacterial infections and mycoses, biology.organism_classification, Oxime, chemistry, Alcohols, Streptococcus pyogenes, Molecular Medicine
Abstract: Alcohol, ketone, aldehyde, and oxime analogues of ambruticin (1) were prepared. The analogues were tested against Histoplasma capsulatum, Microsporum fulvum, Candida albicans, and Streptococcus pyogenes. Structure-activity relationships are described. Increasing the bulk of substituent at C1 and C5 reduces antifungal activity.
Published: 1979
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Author: David T. Connor and M. Von Strandtmann
Subjects: chemistry.chemical_compound, chemistry, Stereochemistry, Organic Chemistry, Benzofuran, Ring (chemistry)
Published: 1973
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Author: J. Shavel, M. Von Strandtmann, Sylvester Klutchko, and A. C. Sonntag
Subjects: chemistry.chemical_compound, Chemistry, Organic Chemistry, Pyrroline, Medicinal chemistry
Published: 1973
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Author: M. Von Strandtmann, A. C. Sonntag, J. Shavel, and Sylvester Klutchko
Subjects: chemistry.chemical_compound, Chemistry, Kornblum–DeLaMare rearrangement, Organic Chemistry, Pyrroline, Sigmatropic reaction, Omega, Medicinal chemistry, Carroll rearrangement
Published: 1973
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