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Your search keyword '"Krzysztof Lewinski"' showing total 4 results
Start Over Author "Krzysztof Lewinski" Publisher american chemical society (acs)
4 results on '"Krzysztof Lewinski"'

1. Stereodivergent Access to Polyhydroxylated 10-Azabicyclo[4.3.1]decanes as New Calystegine Analogues

Author

Vincent Chagnault, Krzysztof Lewinski, Olivier R. Martin, Kyoko Ikeda, Naoki Asano, and Philippe Compain

Subjects
Models, Molecular, chemistry.chemical_classification, Molecular Structure, Bicyclic molecule, Stereochemistry, Organic Chemistry, Stereoisomerism, Bridged Bicyclo Compounds, Heterocyclic, Metathesis, Polyol, chemistry, Nucleophile, Cyclization, Organic chemistry, Tropanes
Abstract

A rapid and stereodivergent access to polyhydroxylated 10-azabicyclo[4.3.1]decanes as new calystegine analogues by way of a double benzotriazolyl/carbon nucleophile exchange followed by a ring-closing metathesis was achieved. Preliminary evaluation of the new compounds as glucocerebrosidase inhibitors was also performed.

Published
2009

2. Stereoselective synthesis of long-chain polyols by sequential homologation of enals with nonracemic .gamma.-silyloxy allylic stannanes and directed hydroxylation

Author

Krzysztof Lewinski, Serge Beaudoin, and James A. Marshall

Subjects
Hydroxylation, chemistry.chemical_classification, Addition reaction, chemistry.chemical_compound, Allylic rearrangement, chemistry, Polyol, Stereochemistry, Organic Chemistry, Stereoselectivity, Aliphatic compound, Protecting group, Adduct
Abstract

The nonracemic γ-silyloxy allylic stannanes (S)-8 and (R)-8 add to the (R,R)-tartrate derived enals 7 and 24 to afford the adducts alkadienol 9, 14, and alkatetraenediol 25. The bis-TBS derivatives 10, 15 and 22, upon hydroxylation with catalytic OsO 4 -NMO, yield the differentially protected polyols 11, 16, and 24

Published
1993

4. Structure of (urea)mercury(II) chloride and the effects of strain on ligand properties of urea

Author

Krzysztof Lewinski, Lukasz Lebioda, and Jan Sliwinski

Subjects
chemistry.chemical_classification, Strain (chemistry), Chemistry, Ligand, Crystal structure, Inorganic Chemistry, Mercury(II) chloride, Crystallography, chemistry.chemical_compound, X-ray crystallography, Urea, Molecule, Physical and Theoretical Chemistry, Inorganic compound
Abstract

Comparaison entre les structures du chlorure de (uree) mercure et du chlorure de bis(ethyluree) mercure, donnant un exemple de l'effet de deformation, introduite dans la molecule uree par le pont ethylene, sur les proprietes de coordination de l'uree

Published
1983

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