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Your search keyword '"Julio C. Medina"' showing total 18 results

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18 results on '"Julio C. Medina"'

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1. Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere

2. Discovery of a Potent Steroidal Glucocorticoid Receptor Antagonist with Enhanced Selectivity against the Progesterone and Androgen Receptors (OP-3633)

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3. Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101)

4. Discovery and in Vivo Evaluation of the Potent and Selective PI3Kδ Inhibitors 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-0687) and 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-1430)

5. Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic Acid Inhibitor of the MDM2–p53 Interaction

6. Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3Kδ Inhibitors for Inflammation and Autoimmune Disease

7. Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2–p53 Interaction

8. Selective and Potent Morpholinone Inhibitors of the MDM2–p53 Protein–Protein Interaction

9. Improving the Pharmacokinetics of GPR40/FFA1 Full Agonists

10. Discovery and in Vivo Evaluation of Dual PI3Kβ/δ Inhibitors

11. Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist

12. Discovery of AMG 853, a CRTH2 and DP Dual Antagonist

13. Neutral Molecule Receptor Systems Using Ferrocene's 'Atomic Ball Bearing' Character as the Flexible Element

14. Ferrocenyl iron as a donor group for complexed silver in ferrocenyldimethyl[2.2]cryptand: a redox-switched receptor effective in water

15. Redox-switched molecular aggregates: the first example of vesicle formation from hydrophobic ferrocene derivatives

16. A molecular receptor based on the ferrocene system: selective complexation using atomic ball bearings

17. Enzymic cyclization of hydroxylated surrogate squalenoids with bakers' yeast