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Your search keyword '"Jia, Zhihong"' showing total 6 results
Start Over Author "Jia, Zhihong" Publisher american chemical society (acs)
6 results on '"Jia, Zhihong"'

1. One-Pot Protocol to Functionalized Benzopyrrolizidine Catalyzed Successively by Rh2(OAc)4 and Cu(OTf)2: A Transition Metal–Lewis Acid Catalysis Relay

Author

Mei-Hua Shen, Ke Xu, Hua-Dong Xu, Jia Zhihong, and Hao Zhou

Subjects
chemistry.chemical_element, Biochemistry, Catalysis, Rhodium, chemistry.chemical_compound, Transition metal, Polymer chemistry, Organometallic Compounds, Transition Elements, Combinatorial Chemistry Techniques, Organic chemistry, Physical and Theoretical Chemistry, Lewis Acids, Mesylates, chemistry.chemical_classification, Sulfonamides, Molecular Structure, Organic Chemistry, Triazoles, Lewis acid catalysis, Sulfonamide, chemistry, Cyclization, Ylide, Intramolecular force, Methane, Carbene
Abstract

4-N-allylarylpropylamino-1-sulfonyl triazoles are converted to structurally unique benzopyrrolizidinyl sulfonamides in a one-pot operation. Intramolecular capture of rhodium carbene with arylamino nitrogen gives rise to the formation of an ammonium ylide immediate. A [2,3]- or [1,2]-rearrangement occurs to give a 2-allylpyrrolidinyl-2-carbimine intermediate which undergoes Cu(OTf)2 catalyzed aza-Friedel-Crafts cyclization to finish a highly functionalized tricyclic system decorated with a synthetically difficult quaternary carbon center, a sulfonamide group, and an allyl segment.

Published
2014

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