28 results on '"Douglas, Kenneth"'
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2. Biophysical and X-ray Crystallographic Analysis of Mps1 Kinase Inhibitor Complexes,
3. Quantum Dot FRET Biosensors that Respond to pH, to Proteolytic or Nucleolytic Cleavage, to DNA Synthesis, or to a Multiplexing Combination
4. Pre-Steady-State Kinetic Study of Substrate Specificity ofEscherichia coliFormamidopyrimidine−DNA Glycosylase
5. Antitrypanosomal, Antileishmanial, and Antimalarial Activities of Quaternary Arylalkylammonium 2-Amino-4-Chlorophenyl Phenyl Sulfides, a New Class of Trypanothione Reductase Inhibitor, and of N-Acyl Derivatives of 2-Amino-4-Chlorophenyl Phenyl Sulfide
6. Design, Synthesis, and Enzymatic Evaluation of N-Acyloxyalkyl- and N1-Oxazolidin-2,4-dion-5-yl-Substituted β-lactams as Novel Inhibitors of Human Leukocyte Elastase
7. DNA Mismatch Detection by Resonance Energy Transfer between Ruthenium(II) and Osmium(II) Tris(2,2‘-bipyridyl) Chromophores
8. Aminoimidazolylmethyluracil Analogues as Potent Inhibitors of Thymidine Phosphorylase and Their Bioreductive Nitroimidazolyl Prodrugs
9. Self-Assembly of Heterobimetallic d−f Hybrid Complexes: Sensitization of Lanthanide Luminescence by d-Block Metal-to-Ligand Charge-Transfer Excited States
10. Potential Tumor-Selective Nitroimidazolylmethyluracil Prodrug Derivatives: Inhibitors of the Angiogenic Enzyme Thymidine Phosphorylase
11. Thermodynamic, Kinetic, and Structural Basis for Recognition and Repair of 8-Oxoguanine in DNA by Fpg Protein from Escherichia coli
12. Stereochemistry at Phosphorus of the Reaction Catalyzed by myo-Inositol Monophosphatase
13. Stopped-Flow Kinetic Studies of the Interaction between Escherichia coli Fpg Protein and DNA Substrates
14. Experimental Precedent for the Need To Involve the Primary Hydration Layer of DNA in Lead Drug Design
15. Synthetic Inhibitors of the Processing of Pretransfer RNA by the Ribonuclease P Ribozyme: Enzyme Inhibitors Which Act by Binding to Substrate†
16. Use of an Additional Hydrophobic Binding Site, the Z Site, in the Rational Drug Design of a New Class of Stronger Trypanothione Reductase Inhibitor, Quaternary Alkylammonium Phenothiazines
17. Inversion of Configuration during the Hydrolysis of d-1-Sp-myo-Inositol [17O]Thiophosphate Catalyzed by myo-Inositol Monophosphatase
18. Phenothiazine Inhibitors of Trypanothione Reductase as Potential Antitrypanosomal and Antileishmanial Drugs
19. Rational Drug Design Approach for Overcoming Drug Resistance: Application to Pyrimethamine Resistance in Malaria
20. Phenothiazine Inhibitors of Trypanothione Reductase as Potential Antitrypanosomal and Antileishmanial Drugs
21. Predictability of Designing Specific Binding Interactions for DNA Minor Groove Ligands from NMR Spectroscopy and Molecular Modeling: A Copper(II)-Activated DNA Cleaver Based on Hoechst 33258
22. Molecular Design of DNA-Directed Ligands with Specific Interactions: Solution NMR Studies of the Interaction of a m-Hydroxy Analog of Hoechst 33258 with d(CGCGAATTCGCG)2
23. Minor-groove recognition of the self-complementary duplex d(CGCGAATTCGCG)2 by Hoechst 33258: a high-field NMR study
24. Interactions of small ligands with Busycon canaliculatum and Limulus polyphemus hemocyanins as studies by ultraviolet spectrophotometry and proton and fluorine-19 nuclear magnetic resonance
25. Elimination-addition pathways for thiol esters
26. Elimination-addition mechanisms of acyl group transfer: hydrolysis and aminolysis of aryl phenylmethanesulfonates
27. Electrochemical reduction in the synthesis of catechol-derived peptides as potential metal chelators and enzyme inhibitors
28. Chemical and biochemical transfer of acyl groups. A new look at an old mechanism
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