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Your search keyword '"Sielker, Sonja"' showing total 1 results
Start Over Author "Sielker, Sonja" Publisher american chemical society
1 results on '"Sielker, Sonja"'

1. Spectroscopic and biochemical studies on protein variants of quinaldine 4-oxidase: Role of E736 in catalysis and effects of serine ligands on the FeSI and FeSII clusters

Author

Kappl, Reinhard, Sielker, Sonja, Ranguelova, Kalina, Wegner, Jeannine, Parschat, Katja, Huttermann, Jurgen, and Fetzner, Susanne

Subjects
Molybdenum -- Structure, Molybdenum -- Spectra, Iron compounds -- Structure, Iron compounds -- Spectra, Electron transport -- Research, Biological sciences, Chemistry
Abstract

A study used site directed mutagenesis to construct variants of quinaldine 4-oxidase (Qox) with replacement of positions C40, C45, C48, C60, C120, and C154 of [Qox.sub.s] by serine to assess which iron ions of FeSI and FeSII are likely to be involved in intramolecular electron transfer between the molybdenum center and flavin. The properties of the Qox variants when taken collectively reveal that Fe1 of both FeSI and FeSII are the reducible iron sties whereas the Fe2 ions remain in the ferric state.

Published
2006

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