Search

Your search keyword '"Shufen Xu"' showing total 2 results
Start Over Author "Shufen Xu" Publisher american chemical society
2 results on '"Shufen Xu"'

2. Stereoselective Synthesis of 5-Substituted Pyrrolo[1,2-c]imidazol-3-ones: Access to Annulated Chiral Imidazol(in)ium Salts.

Author

Costa Metallinos and Shufen Xu

Subjects
*ASYMMETRIC synthesis, *CHIRALITY, *IMIDAZOLES, *SALTS, *HETEROCYCLIC compounds, *CARBENES, *METAL catalysts, *LOW temperatures
Abstract

A two-step synthesis of N-heterocyclic carbene (NHC) precatalysts by diastereoselective or enantioselective lithiation of pyrrolo[1,2-c]imidazol-3-ones followed by POCl3-induced salt formation is described. The resulting 3-chloro-pyrroloimidazol(in)ium salts may be coordinated to palladium(II) upon NHC generation with t-BuLi at low temperature. The method may facilitate exploitation of these compounds as chiral organocatalysts or ligands in metal catalysis. [ABSTRACT FROM AUTHOR]

Published
2010
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results