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Your search keyword '"Hughes, Dave"' showing total 3 results
Start Over Author "Hughes, Dave" Publisher american chemical society
3 results on '"Hughes, Dave"'

2. A mild and efficient synthesis of 4-quinolones and quinolone heterocycles

Author

Zewge, Daniel, Cheng-yi Chen, Curtis, Deer, Dormer, Peter G., and Hughes, Dave L.

Subjects
Aniline -- Chemical properties, Chemical synthesis -- Analysis, Quinoline -- Chemical properties, Biological sciences, Chemistry
Abstract

The method to cycloacylate aniline derivatives to 4-quinolones in the presence of Eaton's reagent which also be used to prepare host of heterocycles and bis-quinolones is described.

Published
2007

3. Direct N-acetyl enamine formation: lithium bromide mediated addition of methyllithium to nitriles.

Author

Savarin CG, Boice GN, Murry JA, Corley E, DiMichele L, and Hughes D

Abstract

An improved protocol for N-acetyl enamine formation is disclosed which involves LiBr-mediated addition of MeLi to substituted nitriles. The resulting enamides are isolated in high yields and excellent purity which permits subsequent hydrogenation at very low catalyst loading.

Published
2006
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