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Your search keyword '"DOBRITSA, ANATOLY P."' showing total 2 results
Start Over Author "DOBRITSA, ANATOLY P." Publisher american chemical society
2 results on '"DOBRITSA, ANATOLY P."'

1. Structure of Cry3A delta-endotoxin within phospholipid membranes

Author

Loseva, Olga I., Tiktopulo, Elizabeth I., Vasiliev, Victor D., Nikulin, Alexey D., Dobritsa, Anatoly P., and Potekhin, Sergey A.

Subjects
Endotoxins -- Research, Bacillus thuringiensis -- Research, Proteins -- Structure, Structure-activity relationships (Biochemistry) -- Analysis, Biological sciences, Chemistry
Abstract

Research demonstrates that the binding of Cry3A delta-endotoxin to liposomes does not cause structural changes in domain I as revealed by unchanged denaturation activation energy. Furthermore, removal of 4-terminal alpha-helices and C-terminal 56 amino acids does not interfere in the interaction of the toxin with liposomes.

Published
2001

2. Transition state of the rate-limiting step of heat denaturation of Cry3A delta-endotoxin

Author

Potekhin, Sergey A., Loseva, Olga I., Tiktopulo, Elizabeth I., and Dobritsa, Anatoly P.

Subjects
Bacillus thuringiensis -- Research, Proteins -- Denaturation, Endotoxins -- Research, Calorimetry -- Usage, Biological sciences, Chemistry
Abstract

Research was conducted to examine the heat denaturation of Cry 3A delta-endotoxin from Bacillus thuringiensis var. tenebrionis an its 55 kDa fragment using differential scanning microcalorimetry at low pH. The denaturation of Cry3A delta-endotoxin was revealed to be a nonequilibrium process at heating rates ranging between 0.125 to 2 K/min. Results elucidate the nature of the stability of the delta-endotoxin structure at low pH and reveal some structural characteristics of the transition state for the molecule.

Published
1999

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