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Your search keyword '"Blankenship, John W."' showing total 1 results
Start Over Author "Blankenship, John W." Publisher american chemical society
1 results on '"Blankenship, John W."'

1. Probing backbone hydrogen bonds in the hydrophobic core of GCN4

Author

Blankenship, John W., Balambika, Rema, and Dawson, Philip E.

Subjects
Biochemistry -- Research, Hydrogen bonding -- Physiological aspects, Amides -- Physiological aspects, Proteins -- Genetic aspects, Proteins -- Physiological aspects, Esters -- Physiological aspects, Biological sciences, Chemistry
Abstract

Research has been conducted on backbone amide hydrogen bonds. The effect of amide to ester substitution on protein structure stability has been investigated via the study of sequential single ester substitution introduced into the hydrophobic core of GCN4-derived sequence at a and d positions, and the results suggest that backbone engineering via ester substitution can be used in probing backbone hydrogen bond strength.

Published
2002

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