1. Novel Models to Identify Census Tracts for Hepatitis C Screening Interventions.
- Author
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Ludden T, Shade L, Thomas J, de Hernandez BU, Mohanan S, Russo MW, Leonard M, Zamor PJ, Patterson CG, and Tapp H
- Subjects
- Hepatitis C diagnosis, Hepatitis C drug therapy, Hepatitis C transmission, Humans, Prevalence, Risk Factors, United States epidemiology, Censuses, Hepatitis C epidemiology, Mass Screening, Social Determinants of Health
- Abstract
Background: Increased screening efforts and the development of effective antiviral treatments have led to marked improvement in hepatitis C (HCV) patient outcomes. However, many people in the United States are still believed to have undiagnosed HCV. Geospatial modeling using variables representing at-risk populations in need of screening for HCV and social determinants of health (SDOH) provide opportunities to identify populations at risk of HCV., Methods: A literature review was conducted to identify variables associated with patients at risk for HCV infection. Two sets of variables were collected: HCV Transmission Risk and SDOH Level of Need. The variables were combined into indices for each group and then mapped at the census tract level (n = 233). Multiple linear regression analysis and the Pearson correlation coefficient were used to validate the models., Results: A total of 4 HCV Transmission Risk variables and 12 SDOH Level of Need variables were identified. Between the 2 indexes, 21 high-risk census tracts were identified that scored at least 2 standard deviations above the mean. The regression analysis showed a significant relationship with HCV infection rate and prevalence of drug use (B = 0.78, P < .001). A significant relationship also existed with the HCV infection rate for households with no/limited English use (B = -0.24, P = .001), no car use (B = 0.036, P < .001), living below the poverty line (B = 0.014, P = .009), and median household income (B = -0.00, P = .009)., Conclusions: Geospatial models identified high-priority census tracts that can be used to map high-risk HCV populations that may otherwise be unrecognized. This will allow future targeted screening and linkage-to-care interventions for patients at high risk of HCV., Competing Interests: Conflicting and Competing Interests: None, (© Copyright 2020 by the American Board of Family Medicine.)
- Published
- 2020
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